Neural and glandular localisation of substance P inEchinostoma caproni (Trematoda-Digenea)

Richard, Josette; Klein, M. J.; Stoeckel, M. E.

doi:10.1007/bf00930963

Cited by 18 publications

(6 citation statements)

References 15 publications

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“…The present investigation has demonstrated, for the first time, the presence and distribution of immunoreactivity to prolactin in the nervous system in Taenia hydatigena and Taenia solium. The demonstration of a large number of the serotoninergic, cholinergic and peptidergic components of the nervous system in platyhelminths have increased substantially in the last ten years (Gustafsson et al , 1985(Gustafsson et al , , 1993(Gustafsson et al , & 1995Basch & Gupta 1988;Gupta & Basch, 1989;Richard et al, 1989;Maule et al, 1990aMaule et al, & 1993. However, there are extraordinary few data on prolactin in the flatworms, especially in the nervous system of them.…”

Section: Discussionmentioning

confidence: 99%

Prolactin in the Cestodes, Taenia solium and Taenia hydatigena

Liu

Wakuri

Mutoh

1996

Okajimas Folia Anatomica Japonica

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The demonstration of prolactin in cestodes, Taenia solium and Taenia hydatigena, was investigated by using immunocytochemical method. PRL immunoreactivity was widely distributed in the CNS and PNS in the worms. In the scolex PRL-IR perikarya occurred in the cerebral ganglia, around the basic area of the sucker and the rostral border region between the rostellum and the suckers with strong immunoreaction, distinctly in Taenia solium. A number of PRL-IR nerve fibres were observed in the main nerve cords, and a few fibres in the transverse nerve commissure. The holdfast musculature of the scolex was innervated by the PRL-IR fibres. A large number of PRL positive cells with processes and nerve plexuses were seen in the ootype/Mehlis' gland complex, oviduct, the duct of uterum, seminal receptacle and its associated duct, conspicuously in Taenia hydatigena. PRL-IR was evident in the wall of vas efferens of tests and vas deferens. A few PRL positive cells occurred in the medullary parenchyma amongst testes and sent their varicose processes to terminate to the testes. On the wall of the main excretory duct a few PRL-IR cells and fibres were seen.

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Section: Discussionmentioning

confidence: 99%

Prolactin in the Cestodes, Taenia solium and Taenia hydatigena

Liu

Wakuri

Mutoh

1996

Okajimas Folia Anatomica Japonica

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“…The immunocytochemical demonstration of vertebrate like peptides (VIP) have been confined to E. liei Whitfield, 1987and Riddell, et al, 1991). Richard et al (1989) detected substance P-like immunoreactivity in the central and peripheral nervous structures and in the glandular cells of the prostate. Riddell, et al(1991),demonstrated the presence of FMRF amide-like immunoreactive cells in the central nervous system and reproductive system of E. liei.…”

Section: Resultsmentioning

confidence: 94%

HISTOPATHOLOGICAL ALTERATIONS OF Rattus rattus frugivourus INFECTED WITH Echinostoma liei (JEYARASASINGAM, HEYNEMAN, LIM AND MANSOUR,1972 )

Azzam¹,

El–Abd²,

El–Hady³

2015

Journal of Plant Protection and Pathology

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Echinostoma liei (Jeyarasasingam, Heyneman, Lim and Mansour, 1972), was used for the first time as bio control agent for the wild rat Rattus rattus frugivorus Rafinesque. Two levels of infection were used (250 and 500 metacercariae / rat) and histopathological alterations were studied in the affected organs (intestine ,liver and testis). The investigation revealed that high infection of E. liei resulted in severe pathological alteration in rat intestine, and liver, such as edema, lymphocytic infiltration, necrosis and hemorrhage in the liver lead to death in addition to testis hypertrophy with seminiferous tubules devoid of sperms that may lead to sterility. Thus, E. liei could be considered a new effective biological agent for controlling wild rats causing either death or sterility and also safe to human since people in Egypt don't eat fresh water snails either raw or cocked).

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“…In addition, strong NADPH‐d staining was observed in the prostate gland. Richards et al (1989) reported positive immunostaining for substance P in the prostate gland of Echinostoma caproni . According to Vincent (1995), many neuropeptides, including substance P, are coexpressed together with nNOS in vertebrates.…”

Section: Discussionmentioning

confidence: 99%

Comparative study of the spatial relationship between nicotinamide adenine dinucleotide phosphate-diaphorase activity, serotonin immunoreactivity, and GYIRFamide immunoreactivity and the musculature of the adult liver fluke,Fasciola hepatica (Digenea, Fasciolidae)

et al. 2000

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This is the first detailed description of the nitrergic nervous system in a fluke. In this study, the authors analysed the distribution of the nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) reactivity in neuronal and nonneuronal tissues of the adult fluke Fasciola hepatica and compared this with the distribution of the musculature using tetramethylrhodamine isothiocyanate-phalloidin. To assess the correlation between the number of muscle cells in different parts of the fluke and the NADPH-d-stained cells, the nuclei were stained with Hoechst 333 42, which is specific for chromatin. The spatial relation between the NADPH-d-positive nerves and the 5-hydroxytryptamine (serotonin; 5-HT)-immunoreactive (-IR) and GYIRFamide-IR nervous elements was also examined. The methods complement each other. NADPH-d-positive staining occurs in both in neuronal tissue and nonneuronal tissue. Large, NADPH-d-stained neurones were localised in the nervous system. The oral and ventral suckers are innervated with many large NADPH-d-stained neurones. In addition, the NADPH-d staining reaction follows closely the muscle fibres in both the suckers, in the body, and in the ducts of the reproductive organs. The presence of NADPH-d activity along muscle fibres in F. hepatica and in other flatworms supports a possible myoinhibitory role for nitric oxide. Neuronal nitric oxide synthase in flatworms may form a novel drug target, which would facilitate the development of a novel anthelminthic.

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Neural and glandular localisation of substance P inEchinostoma caproni (Trematoda-Digenea)

Cited by 18 publications

References 15 publications

Prolactin in the Cestodes, Taenia solium and Taenia hydatigena

Prolactin in the Cestodes, Taenia solium and Taenia hydatigena

HISTOPATHOLOGICAL ALTERATIONS OF Rattus rattus frugivourus INFECTED WITH Echinostoma liei (JEYARASASINGAM, HEYNEMAN, LIM AND MANSOUR,1972 )

Comparative study of the spatial relationship between nicotinamide adenine dinucleotide phosphate-diaphorase activity, serotonin immunoreactivity, and GYIRFamide immunoreactivity and the musculature of the adult liver fluke,Fasciola hepatica (Digenea, Fasciolidae)

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