Neumonía adquirida en la comunidad: tratamiento de los casos complicados y en situaciones especiales. Documento de consenso de la Sociedad Española de Infectología Pediátrica (SEIP) y Sociedad Española de Neumología Pediátrica (SENP)

Moreno-Pérez, David; Martín, Arturo Sousa; García, Alfredo Tagarro; Montaner, Amparo Escribano; Mulet, J. Figuerola; Garcı́a, Javier; Moreno‐Galdó, Antonio; Lliria, C. Rodrigo Gonzalo de; Lozano, J. Saavedra

doi:10.1016/j.anpedi.2014.12.002

Cited by 18 publications

(8 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…MLs are the first-line treatment for children with MP pneumonia in our country. 44 Fluoroquinolones and tetracyclines are generally avoided in this population due to their side effects, 45 although countries with high rates of ML-resistant strains (such as Japan) have approved tosufloxacin or minocycline as second-line drugs for children with MP pneumonia who respond poorly to MLs. 46 Several studies reporting MLr have been published.…”

Section: Discussionmentioning

confidence: 99%

Macrolide resistance and molecular typing of Mycoplasma pneumoniae infections during a 4 year period in Spain

Rivaya

Jordana‐Lluch

Fernández‐Rivas

et al. 2020

Journal of Antimicrobial Chemotherapy

View full text Add to dashboard Cite

Background Mycoplasma pneumoniae (MP) causes community-acquired pneumonia affecting mainly children, and tends to produce cyclic outbreaks. The widespread use of macrolides is increasing resistance rates to these antibiotics. Molecular tools can help in diagnosis, typing and resistance detection, leading to better patient management. Objectives To assess the MP genotypes and resistance pattern circulating in our area while comparing serological and molecular diagnosis of MP. Methods Molecular and serological diagnosis of MP was performed in 821 samples collected in Badalona (Barcelona, Spain) from 2013 to 2017. Multiple locus variable number tandem repeat analysis (MLVA) and macrolide resistance detection by pyrosequencing were performed in those cases positive by PCR. Presence of respiratory viruses and relevant clinical data were also recorded. Results MP was detected in 16.8% of cases by PCR, with an overall agreement with serology of 76%. Eleven different MLVA types were identified, with 4-5-7-2 (50.1%) and 3-5-6-2 (29.2%) being the most abundant, with the latter showing a seasonal increase during the study. A total of 8% of the strains harboured a point substitution associated with macrolide resistance, corresponding mainly to an A2063G 23S rRNA mutation and directly related to previous macrolide therapy. Analysis of respiratory viruses showed viral coinfections in most cases. Conclusions Serological and molecular tools combined could improve MP diagnosis and the analysis of its infection patterns. Macrolide resistance is associated with previous therapy. Given that MP pneumonia usually resolves spontaneously, it should be reconsidered whether antibiotic treatment is suitable for all cases.

show abstract

Section: Discussionmentioning

confidence: 99%

Macrolide resistance and molecular typing of Mycoplasma pneumoniae infections during a 4 year period in Spain

Rivaya

Jordana‐Lluch

Fernández‐Rivas

et al. 2020

Journal of Antimicrobial Chemotherapy

View full text Add to dashboard Cite

show abstract

“…En caso de sospechar infección por estafilococos añadir Vancomicina, (12) aunque no se expresa así en este estudio en ocasiones se asociaron estos medicamentos pues la Vancomicina es un glicopeptido que penetra bien en el líquido pleural ejerciendo una acción bactericida activa contra Gram positivo. En nuestra investigación encontramos que estos antimicrobianos fueron los más utilizados en el 78.8 y 57.7% de los pacientes.…”

Section: Discussionunclassified

Neumonía grave adquirida en la comunidad en un Servicio de Terapia Pedíatrica

Fonseca

Fonte

Calderón

et al. 2018

PFR

View full text Add to dashboard Cite

Introducción: la neumonía es un proceso inflamatorio del parénquima pulmonar con una prevalencia importante en la infancia, sobre todo en los primeros años de vida, reconocible radiológicamente y expresada en una clínica variada. Objetivos: caracterizar la neumonía grave adquirida en la comunidad en el Servicio de Terapia en el Hospital Pediátrico de San Miguel del Padrón en el período de enero a diciembre de 2015. Material y método: estudio observacional descriptivo de corte transversal en el servicio, Hospital y período antes mencionado. El universo estuvo constituido por 52 pacientes, entre los 29 días y 13 años, con diagnóstico de neumonía grave adquirida en la comunidad según los consensos internacionales y que consintieran los padres o tutores participar de la investigación. Resultados: hubo un claro predominio de los pacientes masculinos (63,5%) y el 85.5% de la población en estudio es menor de 5 años. La fiebre y las manifestaciones respiratorias altas fueron los síntomas más comunes pues estuvieron presentes en el 88.5 y 78.8% de los pacientes respectivamente. Predominó el tiraje, especialmente en los menores de 1año, la polipnea se constató en 29 de los niños. La neumonía derecha predominó y el derrame pleural fue la complicación más frecuente. Un 78.8% de los pacientes fue tratado con Cefotaxima. Conclusiones: en el período en estudio la neumonía grave constituyó una parte significativa entre los ingresos en terapia intensiva, incidiendo mayormente en los niños menores de 5 años.

show abstract

“…Furthermore, cefotaxime appears to be superior when compared to ceftriaxone. Furthermore, intravenous monotherapy is strongly recommended for initial treatment (De Benedictis et al, 2020;Leoni et al, 2020;Moreno-Pérez, et al, 2015).…”

Section: Pleural Effusionmentioning

confidence: 99%

Treatment of complicated bacterial pneumonia in children

Freire,

Souza,

Jucá Neto

et al. 2024

RSD

View full text Add to dashboard Cite

Introduction: Community-acquired pneumonia (CAP) is one of the most common infectious diseases in pediatrics, and may be related to the direct occurrence of local complications such as empyema, necrotizing pneumonia, lung abscess or pleural effusion, which are directly related to worsening of the clinical aspect and prolongation of the hospitalization period. Methodology: A narrative review of the literature was carried out in the PUBMED database, using the following keywords: “Bacterial pneumonia in children”, “Complicated Pneumonia” and “Treatment”, with the time filter for the last 5 years (2019-2023). Results: From the research carried out, 408 articles were identified, of which, after applying inclusion and exclusion criteria, 12 were selected for analysis. Discussion: The main complications are related to specific complementary exams and assertive surgical or antimicrobial therapies that seek to avoid mortality, exacerbation of other complications and reduce hospitalization time and associated morbidities. Conclusion: Knowledge about the complications of community-acquired pneumonia, particularly its course of development and its propaedeutic approach, helps to alleviate the difficulties of the clinical context and provide more security to the doctor in his/her healthcare assistance to the patient.

show abstract

Neumonía adquirida en la comunidad: tratamiento de los casos complicados y en situaciones especiales. Documento de consenso de la Sociedad Española de Infectología Pediátrica (SEIP) y Sociedad Española de Neumología Pediátrica (SENP)

Cited by 18 publications

References 38 publications

Macrolide resistance and molecular typing of Mycoplasma pneumoniae infections during a 4 year period in Spain

Macrolide resistance and molecular typing of Mycoplasma pneumoniae infections during a 4 year period in Spain

Neumonía grave adquirida en la comunidad en un Servicio de Terapia Pedíatrica

Treatment of complicated bacterial pneumonia in children

Contact Info

Product

Resources

About