Periods of time in which stocks of knowledge hold plausible or true are decreasing. At the same time, the amount of information which has to be managed is augmenting -due to technologically increased possibilities of collecting, processing and producing infomation. Taking homoeopathy as an example of a "computer-unlike" domain, the aim of this paper is to shed some light on twoas I will demonstrate -interrelated phenomena: First, the production and application of holistic knowledge is increasingly supported by computers; second, sociological assumptions on gendered styles of using computers need to be reconsidered. Based on extensive qualitative research which I have conducted over the past several years, I argue that the clash of traditional holistic medicine and modem social requirements of treating patients in a way that is "quick and perceptible", computer-supported homoeopathy offers leeways which can be approriated in a manner which I suggest is best understood as a process of de-emphasizing gender (de-gendering). As a consequence, the notion of "women as technological illiterates" has to be reworked thoroughly.