Neue Antipodenpaare zur optischen Spaltung recemischer Basen

Abstract

329set& man mit Wasser, filtrierte und lrristallisierte das Produkt aus Allrohol utn: 650 mg stumpigelbe Nadelchen, Smp. 122"; Amax: 234 (33850), 366 (14990) nm (c).

New technique in optical resolutions

“….2952 (2) .3256 (3) .3586 (2) .3568 (3) .3251 (3) .3332 (3) .3737 (3) .4237 (3) .4178 (2) .427(8) .4762 (3) .5041 (3) .4883 (3) .5513 (4) .5732 (4) .5703 (4) .6076 (4) .5421 (4) .5557 (4) .4962 (3) .4758 (3) .4408 (3) .5041 (3) .5395 (3) .5211 (4) .5698 (4) .4763 (5) .4898 (5) .4156 (5) .3809 (5) .3972 (4) .3482 (4) .2906 (3) .3326 (3) .363 (4) .2380 (4) .2380 (5) .2758 (5) .1906 (7) .1917 (7) .1434 (6) .1069 (6) .1412 (5) .1037 (5) .0958 (4) .1946(8) .2867 (5) .2323 (6) .2820 (6) .0814 (7) .0114 (7) .2519 (6) .1861…”

“….5695(8 -. 0173 (6) .056(8) .1158(8) .173 (1) .146 (1) .263 (2) .304 (2) .302 (1) .373 (1) .247 (1) .278 (1) .047 (2) .053 (4) .049 (2) .039 (3) .0259 (3) .041 (3) .0394 (3) .039 (3) .051 (2) .283 (1) .041 (3) .055 (4) .0574 (4) .075 (5) .1355 (5) .080 (6) .1182 (6) .083 (6) .0635 (6) .062 (5) .0662 (5) .041 (3) .050 (4) .0527 (4) .064 (5) .0356 (4) .073 (5) .1238 (4) .072 (5) .0976 (5) .061 (5) .1123 (4) .049 (4) .070 (3) .071 (5) .064 (5) .103 (7) .1253 (6) .15 (1) .348 ( 1) .15 (1) .254…”

“….1888 (4) .1872 (4) .2623 (3) .2799 (3) .3122 (3) .2558 (4) .2687 (4) .2162 (5) .1990 (5) .1986 (5) .1662 (5) .2212 (4) .2068 (4) .3727 (5) .3473 (5) .4067 (5) .3979 (5) .2742 (4) .2963 (4) .2442 (4) .2451 (4) .5017 (5) .5444 (4) .5264 (4) .6084 (4) .6410 (4) .6312 (7) .6823 (7) .5908(9) .6090(9) .5259 (7) .4933 (7) .4309 (4) .4076 (4) .4126 (4) .4144 (3) .4346 (3) .3426 (3) .3207 (3) .3234 (5) .3324 (3) .4437 (3) .432 (6) .487 (5) . -.…”

“…3833 (9) -.3926(9) -.4969(9) -.322 (1) -.370 (1) -. 1872 (9) -.1326(9) .1237(9) .0545(9) .0651(9) .2010(9) .275 (1) .351 (1) .328 (1) .206 (1) .5188(8) .5862(8) .6387(8) .587 (1) .643 (1) .516 (1) .513 (1) .447 (1) .395 (1) .4482(9) .3926(9) .516 (1) .452 (1) .621 (1) .4589(8) .5322(8) .448 (1) .547 (1) .372 (1) .417 (1) .3209 (6) .29 (1) .35 (1) .078 (6) .0860 (7) .051 (4) .059 (4) .0696 (4) .068 (5) .1211 (5) .086 (6) .0881 (6) .096 (7) .1144 (7) .077 (5) .1716 (5) .076 (5) .0412 (4) .1337 (4) .2547 (4) .078 (5) .0628 (5) .0272 (5) .1057 (5) .075 (4) .073 (5) .1439 (4) .094 (6) .1475…”

N-Demethylation of morphine and structurally related compounds with chloroformate esters

“…The Et20 was removed under reduced pressure to give 0.7 g (yield, 43%) of 7: mp 183-185°( reported mp 185°);19 7 • HC1, mp 309-311°dec (reported mp 309°dec). 19 Received May 24,1971 The sedative-hypnotic activity of some 4(3/f)-qmnaz0" Iones1 prompted us to synthesize a number of the isosteric 4(3//)-pteridinones and to investigate their hypnotic and sedative activities. The existing literature gives only a few examples of preparation of 3-alkyl or 3-aryl substituted 4(3/f)-pteridinones2 '4 and no data at all on their pharmacology.…”