Abstract:Background: Jiawei Ling Gui Zhu Gan Decoction (JW-LZD) is based on Linggui Zhugan Decoction (LZD) and adds eight traditional Chinese medicines: Codonopsis pilosula, Astragalus membranaceus, Yam, Epimedium, Morinda officinalis, Tangerine Peel, Pinellia ternata and Coix Seed, which can be used for the treatment of obesity in the clinical. However, the pharmacological mechanisms of JW-LZD remain unclear. Methods: In this study, we determined the molecular targets and mechanismsinvolved in obesity treatment throug… Show more
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