Network pharmacology and experimental verification reveal the mechanism of Hedysari Radix and Curcumae Rhizoma with the optimal compatibility ratio against colitis-associated colorectal cancer

Zhang, Yugui; Wang, Yanjun; Xin, Erdan; Zhang, Zhuanhong; Ma, Dingcai; Liu, Ting; Gao, Feiyun; Bian, Tiantian; Sun, Yujing; Wang, Maomao; Wang, Zhe; Yan, Xingke; Li, Yuefeng

doi:10.1016/j.jep.2023.117555

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2024

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Cited by 3 publications

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Integrating UHPLC-Q-TOF-MS/MS, network pharmacology, bioinformatics and experimental validation to uncover the anti-cancer mechanisms of TiaoPi AnChang decoction in colorectal cancer

Guo,

Yuan,

Huang

et al. 2024

Journal of Ethnopharmacology

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Integrating UHPLC-Q-TOF-MS/MS, network pharmacology, bioinformatics and experimental validation to uncover the anti-cancer mechanisms of TiaoPi AnChang decoction in colorectal cancer

Guo,

Yuan,

Huang

et al. 2024

Journal of Ethnopharmacology

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Shenling Baizhu Decoction treats ulcerative colitis of spleen-deficiency and dampness obstruction types by targeting ‘gut microbiota and galactose metabolism-bone marrow’ axis

Li,

Zhu,

et al. 2024

Journal of Ethnopharmacology

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Research progress on the influence of traditional Chinese medicine on tumor microenvironment therapy

Gao,

Cao,

Ning

et al. 2024

New Updates in Tumor Microenvironment [Working Title]

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More and more attention has been paid to the tumor microenvironment. The occurrence, development, metastasis, and drug resistance of tumor are closely related to the tumor microenvironment. At the same time, the application of traditional Chinese medicine (TCM) in tumor prevention and treatment has attracted more and more attention due to its regulatory effect on tumor cells and tumor microenvironment. The holistic view and multitarget regulatory view of TCM make it very suitable for the regulation of tumor microenvironment. This article will review the current research status of the molecular mechanism of TCM regulation of tumor microenvironment from three aspects: TCM can reverse the inhibitory phenotype of immune cells, TCM can enhance the immune response to tumor cells, and TCM clinical application.

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Network pharmacology and experimental verification reveal the mechanism of Hedysari Radix and Curcumae Rhizoma with the optimal compatibility ratio against colitis-associated colorectal cancer

Cited by 3 publications

References 74 publications

Integrating UHPLC-Q-TOF-MS/MS, network pharmacology, bioinformatics and experimental validation to uncover the anti-cancer mechanisms of TiaoPi AnChang decoction in colorectal cancer

Integrating UHPLC-Q-TOF-MS/MS, network pharmacology, bioinformatics and experimental validation to uncover the anti-cancer mechanisms of TiaoPi AnChang decoction in colorectal cancer

Shenling Baizhu Decoction treats ulcerative colitis of spleen-deficiency and dampness obstruction types by targeting ‘gut microbiota and galactose metabolism-bone marrow’ axis

Research progress on the influence of traditional Chinese medicine on tumor microenvironment therapy

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