Network analyses reveal which symptoms improve (or not) following an Internet intervention (Deprexis) for depression

Mullarkey, Michael C; Stein, Aliza T.; Pearson, Rahel; Beevers, Christopher G.

doi:10.1002/da.22972

Cited by 15 publications

(9 citation statements)

References 47 publications

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“…This study aims to examine the change in structure of peripartum mental health from the network perspective. Using the network approach, we can go beyond merely looking at how the severity of depressive-anxiety symptoms change ( 20 ) as mothers transit from pregnancy to motherhood. In this study, we sought to study the reinforcing loops among symptoms, thus giving us insights into how the mechanisms of maternal mental health may change with the external circumstances ( 21 ).…”

Section: Introductionmentioning

confidence: 99%

Network Analyses of Maternal Pre- and Post-Partum Symptoms of Depression and Anxiety

et al. 2020

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Background Maternal mental health problems often develop prenatally and predict post-partum mental health. However, the circumstances before and following childbirth differ considerably. We currently lack an understanding of dynamic variation in the profiles of depressive and anxiety symptoms over the perinatal period. Methods Depressive and anxiety symptoms were self-reported by 980 women at 26-week pregnancy and 3 months post-partum. We used network analysis of depressive and anxiety symptoms to investigate if the symptoms network changed during and after pregnancy. The pre- and post-partum depressive-anxiety symptom networks were assessed for changes in structure, unique symptom-symptom interactions, central and bridging symptoms. We also assessed if central symptoms had stronger predictive effect on offspring’s developmental outcomes outcomes at birth and 24, 54, and 72 months old than non-central symptoms. Bridging symptoms between negative and positive mental health were also assessed. Results Though the depressive-anxiety network structures were stable during and after pregnancy, the post-partum network was more strongly connected. The central depressive-anxiety symptoms were also different between prenatal and post-partum networks. During pregnancy, central symptoms were mostly related to feeling worthless or useless; after pregnancy, central symptoms were mostly related to feeling overwhelmed or being punished. Central symptoms during pregnancy were associated with poorer developmental outcomes for the child. Anxiety symptoms were strongest bridging symptoms during and after pregnancy. The interactions between negative and positive mental health symptoms were also different during and after pregnancy. Conclusions The differences between pre- and post-partum networks suggest that the presentation of maternal mental health problems varies over the peripartum period. This variation is not captured by traditional symptom scale scores. The bridging symptoms also suggest that anxiety symptoms may precede the development of maternal depression. Interventions and public health policies should thus be tailored to specific pre- and post-partum symptom profiles.

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Section: Introductionmentioning

confidence: 99%

Network Analyses of Maternal Pre- and Post-Partum Symptoms of Depression and Anxiety

et al. 2020

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“…This hypothesis is supported by a recent meta-analysis of actigraphy data which found that depressed individuals were less active during the day and had longer awakenings in the middle of the night, but not a longer sleep latency, than healthy controls (Tazawa et al, 2019). Further, maintenance insomnia has been found to improve after an Internet-provided treatment for depression, whereas onset and terminal insomnia were not significantly changed (Mullarkey et al, 2020).…”

Section: Hypothesesmentioning

confidence: 81%

What types of insomnia relate to anxiety and depressive symptoms in late life?

Bolstad

Nadorff

2020

Heliyon

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Background: Symptoms of insomnia are associated with symptoms of depression and anxiety in older adults, yet less is known about the relation of specific forms of insomnia (i.e., onset, maintenance, and terminal insomnia) with these symptoms. This study explored how insomnia types related to symptoms of anxiety and depression in older adults. It was hypothesized that onset and maintenance insomnia would have stronger relations to anxiety and depressive symptoms than terminal insomnia. Methods: One-hundred thirty-three older adults (mean age 69, age range 65-89) were recruited using Amazon's Mechanical Turk. Participants completed the Insomnia Severity Index, Geriatric Depression Scale-Short Form, and Geriatric Anxiety Inventory-Short Form. Results: Regression analyses that controlled for the comorbidity between anxiety and depressive symptoms indicated that onset insomnia was the only independent predictor of anxiety symptoms, and maintenance insomnia was the only independent predictor of depressive symptoms, each of which had medium to large effect sizes. Limitations: Our findings are limited by an online, primarily Caucasian, and non-clinical sample as well as the cross-sectional design of the study. Conclusions: Our findings suggest that despite overlap between symptoms of depression and anxiety, insomnia may have different mechanisms of affecting each disorder. Thus, the type of insomnia is clinically relevant and should be assessed when symptoms of anxiety, depression, and/or sleep difficulties are reported.

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“…There were 542 participants who reported childhood trauma in baseline measurement and 294 completed all three measurements. Prior research has suggested that the imputation of missing data may introduce distortions in representing the relationships between variables (Borsboom et al, 2017; Mullarkey et al, 2020). As such, we included the 294 participants who completed all three measurements in our analysis.…”

Section: Methodsmentioning

confidence: 99%

Changes in the networks of complex posttraumatic stress disorder symptoms among Chinese college students with childhood trauma.

Huang,

Chi,

Zhao

et al. 2023

Psychological Trauma: Theory, Research, Practice, and Policy

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Objective: To advance understanding of the development of complex posttraumatic stress disorder (CPTSD) symptoms longitudinally and facilitate future treatments, the present study investigated changes in the network of CPTSD symptoms among Chinese college students with childhood trauma. Method: A longitudinal study was conducted with college students, following them three times at 3-month intervals. CPTSD symptoms were measured using the International Trauma Questionnaire, and childhood trauma was assessed by the revised Adverse Childhood Experiences Scale. The final sample consisted of 294 participants with childhood trauma at baseline measurement (28.9% were males, Mage = 20.76 years). Comparisons of cross-sectional networks and cross-lagged panel network (CLPN) analysis were performed to characterize the features and changes of interactions among CPTSD symptoms. Results: Sense of failure and isolation were the core symptoms in the cross-sectional networks of CPTSD symptoms. The comparison of cross-sectional networks indicated that the global network strength was stable, and no node’s strength centrality and only one edge weight changed significantly from Time 1 (T1) to Time 3 (T3). The findings of the CLPN model reveal that worthlessness, difficulties with intimacy, and flashbacks have the highest out-expected influence. In the T1–T3 network, the strongest edge was from worthlessness to sense of failure. Conclusions: Cross-sectional network analyses and comparisons revealed the characteristics of CPTSD networks at multiple time points, while the CLPN analysis identified the longitudinal dynamics of CPTSD symptoms. These provide insights for designing more targeted intervention plans for college students with childhood trauma.

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Network analyses reveal which symptoms improve (or not) following an Internet intervention (Deprexis) for depression

Cited by 15 publications

References 47 publications

Network Analyses of Maternal Pre- and Post-Partum Symptoms of Depression and Anxiety

Network Analyses of Maternal Pre- and Post-Partum Symptoms of Depression and Anxiety

What types of insomnia relate to anxiety and depressive symptoms in late life?

Changes in the networks of complex posttraumatic stress disorder symptoms among Chinese college students with childhood trauma.

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