Net-like pattern of calcification on plain soft-tissue radiographs in patients with calciphylaxis

Shmidt, Eugenia; Murthy, Naveen S.; Knudsen, John M.; Weenig, Roger H.; Jacobs, M. Amanda; Starnes, Autumn M.; Davis, Mark D. P.

doi:10.1016/j.jaad.2012.05.037

Cited by 65 publications

(48 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Computed tomography can also identify calcified arterioles in the soft tissues as well as calcification of the viscera. These findings and other radiographic findings seen in CUA are summarized in Table 5 (81)(82)(83).…”

Section: Metastatic Calcificationmentioning

confidence: 99%

Cutaneous Manifestations of ESRD

Galperin

Cronin

Leslie

2014

Clinical Journal of the American Society of Nephrology

193

View full text Add to dashboard Cite

SummaryA broad range of skin diseases occurs in patients with ESRD: from the benign and asymptomatic to the physically disabling and life-threatening. Many of them negatively impact on quality of life. Their early recognition and treatment are essential in reducing morbidity and mortality. The cutaneous manifestations can be divided into two main categories: nonspecific and specific. The nonspecific manifestations are commonly seen and include skin color changes, xerosis, half-and-half nails, and pruritus. The specific disorders include acquired perforating dermatosis, bullous dermatoses, metastatic calcification, and nephrogenic systemic fibrosis. This review article describes these conditions and considers the underlying pathophysiology, clinical presentations, diagnosis, and treatment options.

show abstract

Section: Metastatic Calcificationmentioning

confidence: 99%

Cutaneous Manifestations of ESRD

Galperin

Cronin

Leslie

2014

Clinical Journal of the American Society of Nephrology

193

View full text Add to dashboard Cite

show abstract

“…Parfois, on met en évidence des thromboses endovasculaires. Une alternative à la biopsie est l'utilisation des radiographies standards qui permettraient de mettre en évidence des calcifications vasculaires en maille dans les zones atteintes avec une spécificité proche de 90 % [7].…”

Section: Discussionunclassified

Dermolipectomie abdominale et mastectomie bilatérale subtotale dans le cadre d’une calciphylaxie : à propos d’un cas et mise au point

Bennis

Becquart

Aljudaibi

et al. 2015

Annales de Chirurgie Plastique Esthétique

View full text Add to dashboard Cite

“…9,10 Plain radiographs can be used to aid with The American Journal of Medicine, Vol 128, No 10, October 2015 diagnosis, and a perilesional net-like pattern of calcification has a specificity of nearly 90%. 11 Bone scans also have been used as a diagnostic aid and may have a sensitivity up to 97% in patients with clinically apparent calciphylaxis in dialysis patients. 12 However, the sensitivity and specificity of these tests is unknown in NUC.…”

Section: Diagnosismentioning

confidence: 99%

Rapidly Progressive Nonuremic Calciphylaxis in the Setting of Warfarin

Bae

Nambudiri

Bach

et al. 2015

The American Journal of Medicine

View full text Add to dashboard Cite

PRESENTATIONA 63-year-old African American woman presented with multiple painful, violaceous nodules on her lower extremities for the preceding 3 weeks. Her past medical history was notable for mechanical aortic valve replacement 7 years prior, asthma, type 2 diabetes mellitus, congestive heart failure, hyperlipidemia, hypertension, and obesity. Her home medications included warfarin, longstanding low-dose prednisone for severe asthma, calcium, atorvastatin, glipizide, metformin, insulin, ipratropium-albuterol, montelukast, omalizumab, losartan, metoprolol, torsemide, and omeprazole.On physical examination, a 5 Â 6-mm firm, violaceous, tender papule was present on the left superior thigh. A 2 Â 2.5-cm hyperpigmented nodule was present on the left inferior thigh. A 5 Â 3.5-cm painful violaceous plaque with central retiform hypopigmentation was present on the left medial calf (Figure 1). Finally, a firm, tender plaque was present on the right posterior calf. ASSESSMENTA punch biopsy from the left calf showed predominantly concentric calcification of subcutaneous vessels approximately 200-250 mm in diameter ( Figure 2). There was no evidence of other entities in the clinical differential diagnosis including vasculitis, polyarteritis nodosa, warfarin necrosis, necrobiosis lipoidica, or a panniculitis such as erythema nodosum.Serum calcium (9.4 mg/dL), phosphorus (4.0 mg/dL), blood urea nitrogen (27 mg/dL), creatinine (1.3 mg/dL), albumin (3.8 g/dL), 25-hydroxyvitamin D (44 ng/mL), and parathyroid hormone (62 pg/mL) were all within normal limits. The international normalized ratio and prothrombin time were appropriately therapeutic. The patient also was up to date with malignancy screening.On follow-up, the biopsy site demonstrated a pathergic response with poor wound healing and evolution into a Figure 1 Two views of the 5 Â 3.5-cm painful violaceous plaque with central retiform hypopigmentation on the left medial calf.

show abstract

Net-like pattern of calcification on plain soft-tissue radiographs in patients with calciphylaxis

Cited by 65 publications

References 15 publications

Cutaneous Manifestations of ESRD

Cutaneous Manifestations of ESRD

Dermolipectomie abdominale et mastectomie bilatérale subtotale dans le cadre d’une calciphylaxie : à propos d’un cas et mise au point

Rapidly Progressive Nonuremic Calciphylaxis in the Setting of Warfarin

Contact Info

Product

Resources

About