“…Therefore, based on our cited previous reported literatures [13,14,15,16,17,18,24,25,26,27,28,] it indicates that vimentin is a marker of NPCs similar to nestin in CNS, and that GFAP is an accepted marker of astrocyte [16,17,29]. Our results showed that all VCCs in the lateral, the anterior and the posterior horn (outside of the EZ) of the spinal cord of G93A SOD1 transgenic mice overlapped to express GFAP; thus, it is suggested that an increase in the numbers of VCCs represents astrogenesis [30] and an astrocyte regenerative response from VCCs occurred in the spinal cord of ALS disease-like transgenic (G93A SOD1) mice.…”