Nested case-control study on the risk factors of colorectal cancer

Chen, Kun; Cai, Jiajun; Liu, Xiyong; Ma, X; Yao, Ke; Zheng, Shu

doi:10.3748/wjg.v9.i1.99

Cited by 21 publications

(26 citation statements)

References 63 publications

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“…The study population involved all residents aged 30 years or older in 10 small towns, and is described elsewhere [8]. At baseline, the cohort members were invited to screen for CRC using the Reverse Passive Hemagglutination Assay-Fecal Occult Blood Test (RPHA-FOBT) [9].…”

Section: Cohortmentioning

confidence: 99%

Alcohol drinking and colorectal cancer: A population-based prospective cohort study in China

Chen

Jiang

et al. 2005

Eur J Epidemiol

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Section: Cohortmentioning

confidence: 99%

Alcohol drinking and colorectal cancer: A population-based prospective cohort study in China

Chen

Jiang

et al. 2005

Eur J Epidemiol

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“…A reduction of CRC mortality in the Unites States was interpreted as due to an increase in colonoscopies for earlier detection (5,6), and a reduction by 43% in people attending once-only flexible sigmoidoscopy screening in the United Kingdom (7) also reveals a bright future for success in CRC prevention and control. In China, since 1980s, a protocol of CRC screening in Chinese was established and proved by a reduction of CRC mortality with a randomized controlled trial in 2003 (8)(9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

Performance of a Colorectal Cancer Screening Protocol in an Economically and Medically Underserved Population

Cai

Zhang

Zhu

et al. 2011

Cancer Prevention Research

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The performance of combining fecal immunochemical tests (FITs) and a high-risk factor questionnaire (HRFQ) in colorectal cancer (CRC) screening in economically and medically underserved populations is uncertain. This study investigated the performance of a CRC screening protocol of combining FITs and an HRFQ as primary screening methods in a rural Chinese population. A CRC mass screening was conducted using FITs and an HRFQ as the first and colonoscopy as the second stage of screening in Jiashan, [2007][2008][2009]. The target population was 31,963 residents in three communities. The compliance was 84.7% for HRFQ, 76.4% for FITs, and 78.7% for colonoscopy. The detected rates of cancer, adenoma, nonadenomatous polyps, and advanced neoplasm were 2.7%, 14.8%, 5.9%, and 8.9% by FITs, which were higher than those by HRFQ (0.5%, 9.2%, 4.8%, and 3.8%, respectively). There was no significant difference in detected rate for nonadenomatous polyps between FITs and HRFQ. A total of 41.2% adenomas, 53.2% nonadenomatous polyps, and 29.8% advanced neoplasms were detected by HRFQ but missed by FITs. Positive predictive value of the screening protocol of combining FITs and HRFQ for advanced neoplasm was 5.7%, which was higher than FITs alone. Men had a higher prevalence of advanced neoplasm than women. Results indicate that combining FITs and HRFQ as primary screening methods is an efficient CRC screening strategy in economically and medically underserved populations.

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“…Globally, colorectal cancer is one of the major causes of morbidity and mortality leading to approximately 10% of the total cancer cases among both males and females [1,2]. The incidence of colorectal cancer has been increasing all over the world with more than 500,000 cases being diagnosed every year [1].…”

Section: Introductionmentioning

confidence: 99%

“…An increasing trend of colon and rectal cancers have been observed among men and women from the Indian subcontinent, the incidence being about 4 per 100,000 population for both sexes together and is the fifth most common cancer (64,332; 6.3%) in this population [3]. The studies from China and Saudi Arabia have identified various risk factors for colorectal cancer such as age >50 years, male gender, illiteracy, dietary pattern, and genetic factors such as family history of colorectal and other cancers [1,4]. However, there are scant data with regard to this from this coastal region with its unique dietary pattern.…”

Section: Introductionmentioning

confidence: 99%

“…The incidence of colorectal cancer has been increasing all over the world with more than 500,000 cases being diagnosed every year [1]. An increasing trend of colon and rectal cancers have been observed among men and women from the Indian subcontinent, the incidence being about 4 per 100,000 population for both sexes together and is the fifth most common cancer (64,332; 6.3%) in this population [3].…”

Section: Introductionmentioning

confidence: 99%

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Colorectal Cancer and Its Risk Factors Among Patients Attending a Tertiary Care Hospital in Southern Karnataka, India

Aithal

Shetty

Binu

et al. 2017

Asian J Pharm Clin Res

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Objective: The objective of this study is to determine the association between certain sociodemographic and lifestyle factors with colorectal cancer.Methods: This case-control study was conducted using a pre-designed questionnaire among 100 incident colorectal cancer patients and 200 unmatched controls attending a Tertiary Care Hospital in Southern Karnataka. Cases and the controls were interviewed, and details regarding their sociodemographic factors were collected. Information on lifestyle factors such as dietary habits, physical activity levels, and substance use were documented. They were also assessed for the presence of existing comorbidities and family history of colorectal and other cancers. Multivariable logistic regression was performed to determine the association between various risk factors and colorectal cancer. Results:In the present hospital-based study, mean age of the participants was <55 years. About 63% of the cases and 54.5% of the controls were males. On multivariable analysis, age ≥50 years (odds ratio [OR]=1.87; 95% confidence interval [CI]=1.02-3.45), low physical activity (OR=5.66; 95% CI=3.10-10.34) and low frequency of fruits consumption (OR=4.10; 95% CI=2.21-7.50), and hypertension (OR=4.65; 95% CI=1.32-16.44) showed a positive association with colorectal cancer. Conclusion:Promoting healthy dietary practices and physical activity among the middle-aged population appears to be significant in the context of colorectal cancer prevention in the Indian subcontinent.

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Nested case-control study on the risk factors of colorectal cancer

Abstract: The study suggested that mucous blood stool history and mixed sources of drinking water were the risk factors of colon cancer and rectal cancer. There was no any significant association between dietary habits and the incidence of colorectal cancer.

Cited by 21 publications

References 63 publications

Alcohol drinking and colorectal cancer: A population-based prospective cohort study in China

Alcohol drinking and colorectal cancer: A population-based prospective cohort study in China

Performance of a Colorectal Cancer Screening Protocol in an Economically and Medically Underserved Population

Colorectal Cancer and Its Risk Factors Among Patients Attending a Tertiary Care Hospital in Southern Karnataka, India

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