Nervus medianus evoked potentials and bispectral index during repeated transitions from consciousness to unconsciousness †

Rundshagen, I.; Mast, Jeffrey W.; Mueller, Noomi; Pragst, F.; Spies, Claudia; Cortina, Kai S.

doi:10.1093/bja/aen186

Cited by 5 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Propofol has been found to lead to a suppression of < 10% of the SSEP amplitude, but can increase the latency of especially the middle latency responses. 11,12 Midazolam and opioids have a moderate effect on SSEP amplitude and latency. 11,[13][14][15] Of note, remifentanil can suppress the cortical SSEP components by 20 to 80% when given in high dosage (0.8 μg/kg/min), as used during neuromonitoring in the operating room.…”

Section: Disturbing Factors and Sedationmentioning

confidence: 99%

Somatosensory Evoked Potentials in Patients with Hypoxic-Ischemic Brain Injury

Horn

Tjepkema-Cloostermans

2017

Semin Neurol

View full text Add to dashboard Cite

Predicting the future of patients with hypoxic-ischemic encephalopathy after successful cardiopulmonary resuscitation is often difficult. Registration of the median nerve somatosensory evoked potential (SSEP) can assist in the neurologic evaluation in these patients. In this article, the authors discuss the principles, applications, and limitations of SSEP registration in the intensive care unit, with a focus on prognostication. Registration of the SSEP is a very reliable and reproducible method, if it is performed and interpreted correctly. During SSEP recordings, great care should be taken to improve the signal-to-noise ratio. If the noise level is too high, the peripheral responses are abnormal or the response is not reproducible in a second set of stimuli; therefore, interpretation of the SSEPs cannot be done reliably. A bilaterally absent cortical SSEP response is a very reliable predictor of poor neurologic outcome in patients with HIE. It has a high specificity, but a low sensitivity, indicating that present cortical responses are a weak predictor of a good recovery. Further research is being done to increase the sensitivity. Somatosensory evoked potentials can be used in a multimodal approach for prognostication of outcome.

show abstract