Nerve ultrasound abnormalities mirror the course of varicella zoster virus sensory–motor radiculoplexopathy

Salvalaggio, Alessandro; Cacciavillani, Mario; Visentin, Andrea; Campagnolo, Marta; Trentin, Livio; Briani, Chiara

doi:10.1002/mus.25494

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…93,94 VZV in NHL with severe motor involvement has also been described. 95 The nerve roots may be affected due to leptomeningeal spread of lymphoma itself, generally NHL. [96][97][98] Radicular pain (in one or more segments) is almost always present, and often asymmetric, and may be associated with spinal cord symptoms secondary to spine compression.…”

Section: Spinal Nerve Rootsmentioning

confidence: 99%

Peripheral nervous system involvement in lymphomas

Briani

Visentin

Campagnolo

et al. 2019

J Peripheral Nervous Sys

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The peripheral nervous system may be involved at any stage in the course of lymphoproliferative diseases. The different underlying mechanisms include neurotoxicity secondary to chemotherapy, direct nerve infiltration (neurolymphomatosis), infections, immune‐mediated, paraneoplastic or metabolic processes and nutritional deficiencies. Accordingly, the clinical features are heterogeneous and depend on the localization of the damage (ganglia, roots, plexi, and peripheral nerves) and on the involved structures (myelin, axon, and cell body). Some clinical findings, such a focal or diffuse involvement, symmetric or asymmetric pattern, presence of pain may point to the correct diagnosis. Besides a thorough medical history and neurological examination, neurophysiological studies, cerebrospinal fluid analysis, nerve biopsy (in selected patients with suspected lymphomatous infiltration) and neuroimaging techniques (magnetic resonance neurography and nerve ultrasound) may be crucial for a proper diagnostic workup.

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