Nerve Tumors

Pronator Syndrome Due to Schwannoma

“…The 'target sign' is an image with central low signal intensity and peripheral high signal intensity on T2-weighted images. This sign may be seen in 15-54 % of Schwannomas and 50-70 % of neurofibromas [10,11]. In the current case, MRI did not demonstrate the typical 'target sign', but MRI contributed to the diagnosis by delineating the anatomical relationship of the tumour and the surrounding muscles and neurovascular structures.…”

“…Schwannoma or neurilemmoma is a benign tumour of the myelinating Schwann cells of the nerve sheath [10][11][12][13]. Schwannoma is the most common tumour of the peripheral nerves [7].…”

“…Immunoreactivity on S-100 immunohistochemistry staining confirmed that the origin of the spindle cells was the Schwann cells. Malignant transformation of Schwannomas is a rare occurrence [6][7][8][10][11][12][13].…”

“…The median nerve may be also compressed by space occupying lesions in the antecubital region [6][7][8][9]. Schwannoma or neurilemmoma is a benign tumour of the myelinating Schwann cells of the nerve sheath [10][11][12]. This report describes a rare case of pronator syndrome due to Schwannoma of the median nerve in the antecubital region.…”

Tumors of the Nervous System

“…150,151 In comparison, most peripheral nerve tumors in dogs are aggressive and tend to recur following surgical excision. However, the vast majority of peripheral nerve tumors in humans are biologically benign (most are schwannomas and neurofibromas).…”