Nerve Pressure Pain Hypersensitivity and Upper Limb Mechanosensitivity in Breast Cancer Survivors: A Case–Control Study

Caro-Morán, Elena; Díaz‐Rodríguez, Lourdes; Cantarero‐Villanueva, Irene; Galiano‐Castillo, Noelia; Arroyo-Morales, Manuel; Fernández-Lao, Carolina

doi:10.1111/pme.12567

Cited by 22 publications

(23 citation statements)

References 43 publications

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“…In a sample of BCS suffering from chronic pain ( n = 305), 59% presented allodynia, and referred to pain sensitization following normally non‐painful stimulation (Hamood, Hamood, Merhasin, & Keinan‐Boker, ). Further studies have suggested an increased sensitivity to pain in the upper limb as a sign of CS mechanism in women after standard treatment of BC (Caro‐Morán et al., ), including mastectomy (Fernández‐Lao et al., ). Another study analyzed pressure pain sensitivity threshold through pressure algometry, allowing to obtain topographical pressure sensitivity maps from the shoulder region in BCS.…”

Section: Discussionmentioning

confidence: 99%

Central sensitization in breast cancer survivors

Cuesta-Vargas

Roldán-Jiménez

Pajares

et al. 2018

J Appl Biobehavioral Res

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The goal of this study was to study central sensitization (CS)‐related symptoms in breast cancer (BC) survivors and to find if there are differences in clinical and functional variables. In this cross‐sectional study, 25 women aged between 32 and 69 years participated. CS pain was measured with the Central Sensitization Inventory (CSI). Forty points was considered the cutoff value. Cancer‐related fatigue (CRF), Quality of life, functional capacity, and handgrip strength (HGS) was assessed. A 60% of BC survivors showed a CSI score from 0 to 40, while the rest 40% of women had a score higher than 40, CSI scores being 38.35 ± 14.54 points in the whole sample. Significant differences were found in functional capacity, CRF and QoL (p < .011). However, there were no differences in HGS (p = .089). This is the first study to report BC survivors CS‐related symptoms. The high CS‐related symptoms group showed differences in some symptoms and functional capacity in this population. Future research including a wider sample and more variables related to pain should be carried out.

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Section: Discussionmentioning

confidence: 99%

Central sensitization in breast cancer survivors

Cuesta-Vargas

Roldán-Jiménez

Pajares

et al. 2018

J Appl Biobehavioral Res

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“…Bilateral deficits in neural mechanosensitivity in women with unilateral BrCA suggest widespread, generalized hypersensitivity. 42,43 Additionally, alterations in body image are common with BrCA 16 and may be more generalized to both breasts rather than just the affected side. Further research into mechanisms for widespread alterations in body image and LRJT performance after BrCA is warranted.…”

Section: Impairments In Lrjt Performancementioning

confidence: 99%

Left/Right Judgment Task for the Chest Region, Part 1: Performance Outcomes in Healthy Women Compared to Women Post Breast Cancer Treatment

Boyd

Smoot

Nee

2022

Rehabilitation Oncology

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Background: Movement planning and execution involve using our internal representations within motor and sensory areas of our brain. Left/right judgment tasks (LRJTs) are behavioral tests that involve determining the side of the body when shown an image, without performing the movement. Individuals theoretically need to use their working body schemas to complete LRJTs. Objectives: To develop a chest LRJT testing protocol and document performance in healthy women and women post breast cancer (BrCA) treatment. Design: Observational, cohort study. Method: We recruited women with and without a history of unilateral BrCA. Participants provided demographic and health history information online, followed by hand, shoulder, and chest LRJTs. Images were digitally mirrored to create equal numbers of left and right images. Images were presented in random order within each body region. We measured accuracy and response time for LRJTs. Results: A total of 316 healthy women and 160 women post-BrCA treatment competed all testing.The BrCA group was consistently slower and less accurate at performing LRJTs for all 3 regions. The side of the image presented was not associated with performance. Conclusions: We successfully developed a chest LRJT testing method. Performance on LRJT of the upper quarter is diminished after BrCA treatment. We established tolerance intervals for anticipated performance in healthy women for future clinical and research comparisons.

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“…Axillary treatment for breast cancer, which is surgical removal of the lymph nodes in the armpit (axilla) or axillary radiotherapy, can contribute to upper limb dysfunction (ULD). Symptoms of ULD include pain, numbness, decreased shoulder range of motion (ROM), reduced strength, joint restrictions, axillary web syndrome (lymphatic cording), and development of arm volume changes or lymphoedema due to interruption or damage to the axillary lymphatic system [ 1 – 7 ]. Severity of symptoms and prevalence vary considerably because of differences in diagnostic criteria, assessment methods and time points among studies.…”

Section: Introductionmentioning

confidence: 99%

A user-centred approach to developing bWell, a mobile app for arm and shoulder exercises after breast cancer treatment

et al. 2017

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PurposeThe study aim was to develop a mobile application (app) supported by user preferences to optimise self-management of arm and shoulder exercises for upper-limb dysfunction (ULD) after breast cancer treatment.MethodsFocus groups with breast cancer patients were held to identify user needs and requirements. Behaviour change techniques were explored by researchers and discussed during the focus groups. Concepts for content were identified by thematic analysis. A rapid review was conducted to inform the exercise programme. Preliminary testing was carried out to obtain user feedback from breast cancer patients who used the app for 8 weeks post surgery.ResultsBreast cancer patients’ experiences with ULD and exercise advice and routines varied widely. They identified and prioritised several app features: tailored information, video demonstrations of the exercises, push notifications, and tracking and progress features. An evidence-based programme was developed with a physiotherapist with progressive exercises for passive and active mobilisation, stretching and strengthening. The exercise demonstration videos were filmed with a breast cancer patient. Early user testing demonstrated ease of use, and clear and motivating app content.ConclusionsbWell, a novel app for arm and shoulder exercises, was developed by breast cancer patients, health care professionals and academics. Further research is warranted to confirm its clinical effectiveness.Implications for cancer survivorsMobile health has great potential to provide patients with information specific to their needs. bWell is a promising way to support breast cancer patients with exercise routines after treatment and may improve future self-management of clinical care.Electronic supplementary materialThe online version of this article (doi:10.1007/s11764-017-0630-3) contains supplementary material, which is available to authorized users.

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Nerve Pressure Pain Hypersensitivity and Upper Limb Mechanosensitivity in Breast Cancer Survivors: A Case–Control Study

Abstract: Breast cancer survivors present bilateral and widespread neural hypersensitivity, as they did in muscular tissue in previous studies. Breast cancer survivors demonstrate a reduction in ROM during ULNTs in the affected side.

Cited by 22 publications

References 43 publications

Central sensitization in breast cancer survivors

Central sensitization in breast cancer survivors

Left/Right Judgment Task for the Chest Region, Part 1: Performance Outcomes in Healthy Women Compared to Women Post Breast Cancer Treatment

A user-centred approach to developing bWell, a mobile app for arm and shoulder exercises after breast cancer treatment

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