Nephrotoxicity and Nephroprotective Potential of African Medicinal Plants

Ekor, Martins

doi:10.1016/b978-0-12-800018-2.00012-1

Cited by 5 publications

(5 citation statements)

References 159 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the adverse health effects of the consumption and usage of T&CM can cause medical illnesses such as nephrotoxicity, hepatoxicity, cardiotoxicity, neurotoxicity, and skin toxicity (10). Several studies have proven that some herbal plants can cause kidney disease (11)(12)(13) and herbal-induced liver injury (14)(15)(16). A study by Jatau and co-workers also found that some patients seeking treatment at the emergency department had a history of using T&CM for their health care (17).…”

Section: Tandcm Practices Recognised In Malaysia Includementioning

confidence: 99%

Awareness on Traditional and Complementary Medicine among Undergraduate Students in Universiti Putra Malaysia

Sahanudin,

Abdullah

2023

MJMHS

View full text Add to dashboard Cite

Introduction: In Malaysia, the use of Traditional and Complementary Medicine (T&CM) for health maintenance is growing yearly. However, the public might not be aware that the usage of T&CM could have an effect if misused. Objective: This study aims to determine the level of knowledge, attitude, practice, and awareness of T&CM among Health Sciences (HS) and Non-Health Sciences (NHS) students at Universiti Putra Malaysia (UPM). Methods: A self-administered online questionnaire was distributed to undergraduate students in UPM through student’s group chat application. Results: There were no significant differences between HS and NHS students’ knowledge, attitude and practice. However, the level of awareness between the two groups were significantly different (HS: 10.07 ± 1.37, NHS: 9.63 ± 1.62) with p<0.01. The main sources to obtain the information for T&CM were family or friends (77.4%), the internet (77.4%), and mass media (59.2%). Common T&CM used were aromatherapy (55.9%), prayer or spiritual healing (73.6%), and traditional herbal (64.1%). Patterns of usage for the above modalities were observed with aromatherapy (5.8%) and traditional herbal (4.8%) highest for weekly, whereas prayer or spiritual healing has the highest for daily usage (32.2%). Conclusion: Students exhibit adequate knowledge, demonstrate a positive attitude and good practice, and have a higher awareness of T&CM. It is recommended for repeated cross-sectional studies to be conducted on the same respondents to track changes in their knowledge, attitude, practice, and awareness of T&CM over time.

show abstract

Section: Tandcm Practices Recognised In Malaysia Includementioning

confidence: 99%

Awareness on Traditional and Complementary Medicine among Undergraduate Students in Universiti Putra Malaysia

Sahanudin,

Abdullah

2023

MJMHS

View full text Add to dashboard Cite

show abstract

“…However, there is debate on whether a khat leaf is a drug plant or a stimulant plant. Many scholars are overviewed leafed consumption results in subjective, mental stimulation, increased physical endurance, increased self-esteem, and social interaction and it is commonly used as a recreational substance [14].…”

Section: Definition and Conceptsmentioning

confidence: 99%

Impact of Khat Production and Marketing on the Livelihood of Smallholder Households in Ethiopia

Dawide¹,

Zeleke²,

Ebro³

2022

View full text Add to dashboard Cite

show abstract

“…The ongoing quest for natural remedies may stem from patients' disappointment with the efficacy of standard treatments. Moreover, according to some beliefs, the use of plants guarantees a healthier lifestyle and that medicinal plants, being natural, seem to be « harmless » (Ekor, 2014).…”

Section: Introductionmentioning

confidence: 99%

Acute and subacute toxicity of the aqueous extract of the leaves of Annona senegalensis Pers. (Annonacee) in rats and mice

2024

Int. J. Biosci.

View full text Add to dashboard Cite

Annona senegalensis pers. is used in Africa for therapeutic and dietary purposes. However, few studies have been carried out in Burkina Faso on the toxicity of this plant's leaves. The aim of the study was to assess the acute and subacute toxicity of the aqueous extract of the leaves of Annona senegalensis on female rats and mice.The acute toxicity study was carried out on six female mice. The control group, received distilled water and the the test group received the extract at a single dose of 2000 mg/ kg bw. After administration, animals were observed for 14 days. For subacute toxicity, thirty female rats were used. The control group received distilled water. The test groups received Annona senegalensis extract at doses of 40, 100 and 200 mg/kg bw respectively for 28 consecutive days. Satellite groups were used. In the acute test, no sign of toxicity or mortality were recorded. The LD50 of the extract is therefore greater than 2000 mg/kg. In the sub-acute test, the body weight of treated rats increased (p> 0.05) compared to the control. Hematological analyses of white and red blood cell and platelet counts showed no significant variations (p> 0.05) compared with the control. Biochemical analyses showed no significant variations (p> 0.05) compared with the control. Histological sections showed no tissue damage in the liver and kidneys of rats treated with extract compared with the control. Our results show that the leaves of Annona senegalensis were non-toxic.

show abstract

Nephrotoxicity and Nephroprotective Potential of African Medicinal Plants

Cited by 5 publications

References 159 publications

Awareness on Traditional and Complementary Medicine among Undergraduate Students in Universiti Putra Malaysia

Awareness on Traditional and Complementary Medicine among Undergraduate Students in Universiti Putra Malaysia

Impact of Khat Production and Marketing on the Livelihood of Smallholder Households in Ethiopia

Acute and subacute toxicity of the aqueous extract of the leaves of Annona senegalensis Pers. (Annonacee) in rats and mice

Contact Info

Product

Resources

About