2009
DOI: 10.3949/ccjm.76a.09043
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Nephrolithiasis: Treatment, causes, and prevention

Abstract: Factors that promote stone formation include low daily urine volumes; saturation of the urine with calcium, oxalate, calcium phosphate, uric acid, or cystine; acidic urine; and bacterial infection. The author identifies the mechanisms of stone formation and outlines management aimed at preventing recurrences.

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Cited by 86 publications
(57 citation statements)
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“…[11] In relevant studies performed, the prevalence of urinary system stone disease has been reportedly ranged between 2, and 20 percent. [1][2][3][7][8][9] The reason for discrepancies between data on the prevalence of stone disease can be explained by inclusion of participants living both in urban, and rural areas in the study, higher number of male participants over a certain age, and conduction of the study in selected groups. In a study performed by Stamatelou et al [9] in USA, in the years 1976-1980, and 1988-1994, a total of 15,364, and 16115 cases were investigated respectively, and increases in the prevalence of stone disease in all decades were reported.…”
Section: Discussionmentioning
confidence: 99%
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“…[11] In relevant studies performed, the prevalence of urinary system stone disease has been reportedly ranged between 2, and 20 percent. [1][2][3][7][8][9] The reason for discrepancies between data on the prevalence of stone disease can be explained by inclusion of participants living both in urban, and rural areas in the study, higher number of male participants over a certain age, and conduction of the study in selected groups. In a study performed by Stamatelou et al [9] in USA, in the years 1976-1980, and 1988-1994, a total of 15,364, and 16115 cases were investigated respectively, and increases in the prevalence of stone disease in all decades were reported.…”
Section: Discussionmentioning
confidence: 99%
“…Men have generally a higher risk of suffering from recurrent renal stone disease In other words, recurrence rates within the first 1-2, 5, and 10 years after diagnosis of renal stone disease are 10-25%, 35%, and 60%, respectively. [2] According to the guidelines of European Association of Urology (EAU), in the management of renal stones, treatment alternatives include watchful waiting, extracorporeal shock wave lithotripsy (ESWL), retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PNL), and open nephrolithotomy. [3] In addition to complaints of severe pain, stress, and anxiety because of development of renal failure, and pyelonephritis, urinary system stone disease can incur serious economic losses.…”
Section: Introductionmentioning
confidence: 99%
“…Most commonly, these stone episodes can cause renal colic resulting in flank or abdominal pain, urinary urgency or frequency, fevers or chills, nausea or vomiting, and gross or microscopic hematuria. 7,8 The incidence of microhematuria and urolithiasis has been estimated to be as high as 90% in the literature and has been theorized to be present when the patient's pain is at its maximum intensity, diminishing to undetectable levels as the pain subsides. 9,10 The absence of hematuria, however, does not always exclude the possibility of urinary lithiasis.…”
Section: Introductionmentioning
confidence: 99%
“…Wichtigste Maßnahme zur Vorbeugung eines rezidivierenden HWI und einer infektbedingten Steinbildung ist die Erhö-hung der Diurese durch eine ausreichende und möglichst regelmäßige Flüssigkeits-zufuhr [11]. Erreger werden am Aufsteigen im Harntrakt gehindert und ausgespült, bevor sie sich im Harntrakt festsetzen und nach erfolgreicher Harnalkalisierung die Steinbildung auslösen können.…”
Section: Therapieansätzeunclassified