Nepehinol - a new Triterpene fromNepeta Hindostana

Abstract

A new triterpene, nepehinol, has been isolated from the medicinal plant NEPETA HINDOSTANA. The structure 3beta-hydroxy-18beta, 19alpha H-lup-20 (19)-ene has been suggested for it.

Pentacyclic triterpene 5‐phenylpenta‐2,4‐dienoyl esters from Peltastes peltatus (Vell.) Woodson

“…In addition, this spectrum confirmed the presence of the 5-phenylpenta-2,4dienoyloxy group (Table 2), as shown above for 1 and 2. The EIMS spectrum of this compound showed the base ion peak at m/z 157 ([C 6 H 5 (CH=CH) 2 CO] + ), related to that of 1, and similar fragmentation pattern to that shown for lupeol [m/z 218 (56%), 203 (25%), 190 (25%), 189 (35%)] for the triterpene part of the molecule (Ahmad et al, 1985). The esterification in the β-position at C-3 was assumed by comparison of the chemical shift of H-3 (δ 4.56) as well as the carbon chemical shifts of C-3 (δc 80.8), C-2 (δc 23.7) and C-4 (δc 38.0) of this compound with that of 1, and to 3β-O-acetyl and 3β-O-cinnamoyl triterpene derivatives in the literature (Sobrinho et al, 1991;Barreto et al, 1998).…”

“…The 1 H-NMR spectrum (Table 1) of 3 showed two signals at δ 4.60 (1H, br s) and 4.70 (1H, br s) and a three hydrogen broad singlet at δ H 1.68 due to a isopropylidene group, suggestive of the presence of a lup-20(29)-ene system in 3 (Ahmad et al, 1985;Jain and Yadava, 1994).…”

Chemical constituents fromClerodendron serratum

“…The oil in column chromatography led to the isolation of compounds 1 and 2. Compound 1 was identified as lupeol by comparing its melting point and spectral data (IR, NMR, and MS) and its monoacetate with literature values [12] and running co-TLC of the monoacetate with an authentic sample.…”

Conferols A and B, New Anti-inflammatory 4-Hydroxyisoflavones from Caragana conferta

“…3) E-cinnamic acid (4), 4) tetracosyl 3,4-dihydroxy-E-cinnamate (5), 5) 8) stigmastrerol (9) 9,10) and lupeol (10), 11) and are also isolated for the first time from this species. The compounds 1-3 showed significant anti-inflammatory activity in respiratory burst assay.…”