Neopterin-Imprinted Columns for Selective Neopterin Recognition from Serum and Urine Samples

Özdaş, Sibel; Peşint, Gözde Baydemir; Arısoy, Pırıl; Zenger, Okan; Eren, Burcu

doi:10.1016/j.procbio.2021.05.022

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…The supporting information contains further figures and explanations related to this study. Additional references cited in Supporting information [17,18,[40][41][42]…”

Section: Supporting Information Summarymentioning

confidence: 99%

Ferric Ions Modulated Carbon Dots as a Fluorescent Probe for the Detection of Neopterin: An Inflammatory Prognostic Marker for Risk Prediction and Severity of Covid‐19

Anju,

Asokan,

Varghese

et al. 2023

ChemistrySelect

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Neopterin (NPT) is a Guanosine Tri Phosphate (GTP) metabolite produced by activated macrophages and is considered a proinflammatory and atherosclerotic agent. Beyond this NPT is a multi-utility biomarker for assessing the status of various diseases including cardiovascular disease, depression, and malignant tumors as well as infections including viral and bacterial origin. Recent clinical investigations suggest the use NPT as a prognostic marker for the early prediction of the severity of Covid-19, which is the prime concern of global public health. One of the main immunopathological characteristics of Covid-19 is an excessive inflammatory response, and the severity of the infection is linked with macrophage activation syndrome (MAS). Hence the assessment of neopterin serves as an effective diagnostic tool for the risk prediction of Covid-19. We present a fluorescence turn-on sensor for neopterin using ferric ion-modulated sulfur and nitrogen co-doped carbon quantum dots. The linear detection of NPT was achieved with a limit of detection of 3.11 nM.

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“…The supporting information contains further figures and explanations related to this study. Additional references cited in Supporting information [17,18,[40][41][42]…”

Section: Supporting Information Summarymentioning

confidence: 99%

Ferric Ions Modulated Carbon Dots as a Fluorescent Probe for the Detection of Neopterin: An Inflammatory Prognostic Marker for Risk Prediction and Severity of Covid‐19

Anju,

Asokan,

Varghese

et al. 2023

ChemistrySelect

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“…MIPs are more stable than antibodies, cost-effective, easy to prepare, and resistant to a wide range of pH, solvents, and temperatures [65][66][67]. MIP-SPE has been extensively used in cancer biomarkers detection with excellent efficiency [68][69][70][71].…”

Section: Solid-phase Extractionmentioning

confidence: 99%

MALDI-TOF MS: A Promising Analytical Approach to Cancer Diagnostics and Monitoring

et al. 2023

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Cancer remains the second most common cause of death after cardiovascular diseases, accounting for nearly 10 million deaths in 2020. Although the incidence of cancer increases considerably with age, the cancer burden can also be reduced and have a high chance of cure through early detection, appropriate treatment, and care of patients. The development of high-throughput analytical approaches, like matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), contributes to identifying a pool of proteins/peptides as putative biomarkers for the early detection, diagnosis, and tumor progression. The purpose of the current review is to present an updated outline of recent proteome/peptidome research to establish putative cancer biomarkers using MALDI-TOF MS and highlight the applicability of statistical analysis in the oncology field. The pros and cons of MALDI-TOF MS application on cancer diagnostics and monitoring will be discussed, as well as compared with tandem mass spectrometry (MS/MS)-based proteomics (e.g., liquid chromatography–tandem mass spectrometry). In addition, pre-analytical (e.g., sample quality control) and analytical (e.g., sample pre-treatment, instrumental analytical conditions) properties that influence the robustness of MALDI-TOF MS data will be also discussed.

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Neopterin imprinted nanofilm decorated SPR sensors: Sensitive neopterin detection from human serum

Eren Yüngeviş,

Baydemir Peşint

2024

Polym. Bull.

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Neopterin-Imprinted Columns for Selective Neopterin Recognition from Serum and Urine Samples

Cited by 6 publications

References 24 publications

Ferric Ions Modulated Carbon Dots as a Fluorescent Probe for the Detection of Neopterin: An Inflammatory Prognostic Marker for Risk Prediction and Severity of Covid‐19

Ferric Ions Modulated Carbon Dots as a Fluorescent Probe for the Detection of Neopterin: An Inflammatory Prognostic Marker for Risk Prediction and Severity of Covid‐19

MALDI-TOF MS: A Promising Analytical Approach to Cancer Diagnostics and Monitoring

Neopterin imprinted nanofilm decorated SPR sensors: Sensitive neopterin detection from human serum

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