Neoplazik Olmayan Kemik Iligi Bozukluklari

Evaluation of Bone Marrow Reconversion in Healthy Adults with Knee MRI

“…The normal bone marrow filling the medullary cavity in the middle of the bones consists of two different type and compositions: the red marrow contains hematopoietic stem cells with 40% fat, %40 water and 20% protein and the yellow bone marrow contains fat-producing and mesenchymal stem cells with 80% fat, 15% water and 5% protein 1,2 . Bone marrow conversion is called the transformation of active red bone marrow to inactive fatty bone marrow occurs in a certain order from the distal to the proximal to the extremities and from the appendix to the axial skeleton and be completed by approximately 25 years of age [3][4][5] . After this age, the red bone marrow is seen only in the axial skeleton, sternum, ribs, humerus and femur metaphyses.…”

“…In cases where hematopoietic bone marrow fails to meet the hematopoiesis requirement, the red bone marrow replaces the yellow bone marrow and called bone marrow reconversion (BMR). BMR can occur not always in pathologic and can be seen in different conditions such smokers, highperformance athletes, anemic individuals, bone marrow replacement diseases, bone marrowstimulating drugs, and obese patients 3,4,6,7 . BMR can be seen noninvasively in daily sequences of magnetic resonance (MR) imaging and radiologists must know the signal characteristics of this physiological process and avoid misdiagnosis.…”