Neoplastic lesions of the appendix

Deans, G. T.; Spence, Roy A. J.

doi:10.1002/bjs.1800820306

Cited by 187 publications

(133 citation statements)

References 107 publications

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“…Our prevalence of 0.62% is comparable to the prevalence rate of 0.5%-0.9% found in other studies in New Zealand and the United Kingdom [1][2][3] . No published reports are available for other predominantly black populations.…”

Section: Discussionsupporting

confidence: 87%

Primary epithelial tumours of the appendix in a black population: A review of cases

Graham¹,

Williams²,

West³

2009

WJG

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AIM:To determine the prevalence, histologic types and clinical features of primary epithelial tumours of the vermiform appendix in a predominantly black population. METHODS:All cases of primary tumours of the appendix identified by review of the histopathology records at the University of the West Indies between January 1987 and June 2007 were selected. Relevant pathologic and clinical data were extracted with supplementation from patient charts where available. Non-epithelial tumours were excluded. The total number of appendectomy specimens over the period was also ascertained. RESULTS:Forty-two primary epithelial tumours were identified out of 6 824 appendectomies yielding a prevalence rate of approximately 0.62%. Welldifferentiated neuroendocrine cell tumours (carcinoids, 47.6%) and benign non-endocrine cell tumours (adenomas, 45.2%) were most common with nearly equal frequency. The median age was 43 years, with no sex predilection. Carcinoid tumours occurred in younger patients (mean age 32 years), with a male-to-female ratio of 1.2:1. A clinical diagnosis of acute appendicitis was the most common reason for appendectomy (57.1%) and was histologically confirmed in 75% (18 of 24) of cases. In total, 16.7% of cases were diagnosed after incidental appendectomy. CONCLUSION:Appendiceal epithelial tumours are rare in our experience, and are represented principally by carcinoid tumours and adenomas. Carcinoid tumours occurred in younger patients but were slightly more common in men than women. Tumours were not suspected clinically and were diagnosed incidentally in specimens submitted for acute appendicitis supporting the need for histological evaluation in all resection specimens.

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Section: Discussionsupporting

confidence: 87%

Primary epithelial tumours of the appendix in a black population: A review of cases

Graham¹,

Williams²,

West³

2009

WJG

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“…However, radiologic findings of appendiceal adenocarcinomas are often dependent on the detection of a resulting mucocele, but a mucocele is only the description of an obstructive mass by intraluminal accumulation of mucoid material and does not contribute to a pathologic diagnosis. The causes of a mucocele may also be benign and only the diameter may suggest the dignity of the process [14,20,21].…”

Section: Discussionmentioning

confidence: 99%

Neuroendocrine Tumour, Mucinous Adenocarcinoma and Signet-Ring Cell Carcinoma of the Appendix: Three Cases and Review of Literature

Ploenes

Börner²,

Kirkpatrick

et al. 2012

Indian J Surg

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Appendiceal neoplasms are relatively common tumours. Although these tumours are often associated with signs and symptoms of acute appendicitis, most appendiceal neoplasms are clinically silent. Appendiceal neoplasms are found in 0.7 to 1.4 per cent of all appendectomy specimens. The classification of these tumours is still confusing and precise treatment methods for these neoplasms remain unclear. First choice therapy of these neoplasms is still a surgical treatment and the type of operative procedure is determined by histology and metatstatic risk. Here, we report three cases of appendiceal neoplasms and make a short review of literature.

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“…[1][2][3] The disease is rare; it is found in less than 0.3% of appendectomies, [8][9][10] more frequently in female patients and, usually, in patients older than 50 years. 8 The size of the mucocele is highly variable, ranging from a few centimeters to very large masses up to 40 cm.…”

Section: Discussionmentioning

confidence: 99%

Giant Mucocele of the Appendix

Francica

Lapiccirella

Giardiello

et al. 2006

Journal of Ultrasound in Medicine

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Objective. Clinical and imaging (sonographic and computed tomographic [CT]) findings in 3 cases of giant mucocele of the appendix are described. Methods. Clinical records of 3 cases of giant mucocele of the appendix were reviewed. All patients had a basal B-mode sonographic examination and a contrast-enhanced sonographic examination using a second-generation low-mechanical index contrast medium. In all cases, a dual-phase spiral CT examination was carried out. Results. In 2 cases, the abdominal masses were discovered in asymptomatic patients; 1 patient had vague abdominal discomfort. A pathologic diagnosis of benign cystoadenoma was found at pathologic examination in all cases, and malignant pseudomyxoma peritonei was disclosed in 1 patient 1 year later. Common sonographic findings were as follows: (1) a huge abdominal mass with a maximum diameter ranging between 20 and 25 cm; (2) a thin hyperechoic border without either solid vegetations or signs of infiltration of surrounding tissues; (3) a complex internal echo structure with anechoic lacunae interspersed between curvilinear, wavy bands of echogenic material (the so-called sonographic onion skin sign); and (4) avascularity of the masses shown on contrast-enhanced sonography with a low-mechanical index medium. At CT, a well-circumscribed cysticlike mass of low attenuation was displayed in all cases. There was lack of enhancement during a dual-phase examination in 2 cases; in the other, a small peripheral area of faint enhancement was appreciated. Only in the latter case could CT reliably assess the origin of the mass. Conclusions. It is suggested that a combination of sonographic (namely the onion skin sign) and CT findings may aid in the correct preoperative diagnosis of giant mucocele of the appendix.

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Neoplastic lesions of the appendix

Cited by 187 publications

References 107 publications

Primary epithelial tumours of the appendix in a black population: A review of cases

Primary epithelial tumours of the appendix in a black population: A review of cases

Neuroendocrine Tumour, Mucinous Adenocarcinoma and Signet-Ring Cell Carcinoma of the Appendix: Three Cases and Review of Literature

Giant Mucocele of the Appendix

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