Neoplastic Diseases

Biology and Diseases of Rabbits

“…Historically, spontaneous neoplasia in the laboratory rabbit has not been widely reported because neoplasia in the rabbit is very uncommon before 2 years of age and many laboratory rabbits are not maintained beyond this age (Weisbroth, 1994). Endometrial adenocarcinoma is the most common tumor in aged female rabbits, with an incidence of 79% reported in a colony of 5-year-old rabbits (Baba and Von Haam, 1972).…”

“…Uterine leiomyomas and leiomyosarcomas are much less common (Weisbroth, 1994). Typically, the disease is present as multiple tumors and is malignant, often metastasizing to the liver, lungs, and other organs.…”

“…Mammary adenocarcinomas are fairly common in older female rabbits and may occur in animals with uterine adenocarcinoma (Weisbroth, 1994). Papillomas have been described, but mammary adenocarcinomas are much more important.…”

“…Seminomas and teratomas have also been reported (Weisbroth, 1994). Interstitial tumors are the most common testicular tumor in the rabbit.…”

Diffuse Cystic Endometrial Hyperplasia and Metastatic Endometrial Adenocarcinoma in a Vietnamese Pot-Bellied Pig (Sus Scrofa)

“…Within the domestic species, endometrial hyperplasia has not been reported to predispose to endometrial carcinomas in cows or dogs. 4,9 Although it is uncertain whether endometrial hyperplasia predisposes to endometrial carcinoma in rabbits, 15 there is little experimental evidence that estrogens promote spontaneous endometrial carcinoma development in this species. 15 Endometrial carcinoma is rare in pigs raised for meat production.…”