Neonatal Varicella Pneumonia: A Rare Presentation

Garg, Dr Abhay

doi:10.18535/jmscr/v5i2.160

Cited by 2 publications

(5 citation statements)

References 6 publications

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“…Neonatal varicella is not a commonly encountered disease, yet it is an important disease we should be able to detect early because it can be fatal in newborns [2,3]. Varicella-zoster virus is the causative agent of this disease.…”

Section: Discussionmentioning

confidence: 99%

“…Neonatal varicella is a rare condition, with the incidence of 2-6 per 100,000 live births per year [1]. Mostly, neonatal varicella is caused from maternal varicella, and the presentation of the disease is variable, ranging from mild symptoms to varicella pneumonia [2,3], hepatitis [2,4], or meningoencephalitis in disseminated disease [5,6]. e worst outcome could be fatal [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…Mostly, neonatal varicella is caused from maternal varicella, and the presentation of the disease is variable, ranging from mild symptoms to varicella pneumonia [2,3], hepatitis [2,4], or meningoencephalitis in disseminated disease [5,6]. e worst outcome could be fatal [2,3]. As maternal viremia happens, the transplacental infection occurs, which may start up to 48 hours before maternal rash develops.…”

Section: Introductionmentioning

confidence: 99%

“…As maternal viremia happens, the transplacental infection occurs, which may start up to 48 hours before maternal rash develops. In neonates born to susceptible mothers who develop varicella symptoms from 4 to 5 days antepartum to 2 days postpartum, the mortality rate of the baby may reach 20-30% [1][2][3]5]. erefore, newborns whose mothers develop varicella 5 days prior to 2 days after birth should receive varicella zoster immunoglobulin (VZIG) in no time.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Intravenous Immunoglobulin and Acyclovir in Preventing Neonatal Varicella

Piyanonpong¹

2020

Case Reports in Infectious Diseases

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Neonatal varicella mostly results from maternal varicella. The disease can cause presentation ranging from mild symptoms to varicella pneumonia, hepatitis, meningoencephalitis, or fatality. If the mother develops symptoms implying varicella 4–5 days antepartum to 2 days postpartum, the mortality rate of the baby may reach 20%. We report a case of neonatal varicella from maternal varicella. The patient’s mother initially developed maculopapular rash over her trunk 1 day after giving birth; she had a family member in the same household diagnosed with herpes zoster recently, and another member with diagnosed varicella, whose rash disappeared before the patient's birth. On the baby's third day of life, discrete vesicular rashes on erythematous background and discrete erythematous maculopapular rashes were found over his trunk, arms, and legs. The baby was subsequently diagnosed with neonatal varicella and was treated by intravenous immunoglobulin (IVIG) because there was no varicella zoster immunoglobulin (VZIG) available in the hospital, and also, intravenous acyclovir was given for 7 days. The rash completely resolved by the baby's fifth day of life, without any complications. The combination of IVIG and acyclovir might not effectively prevent neonatal varicella, but the medication could prevent the baby from developing serious complications and shorten the clinical course.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effects of Intravenous Immunoglobulin and Acyclovir in Preventing Neonatal Varicella

Piyanonpong¹

2020

Case Reports in Infectious Diseases

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“…12 Pneumonia varisela merupakan kondisi yang jarang tetapi menjadi penyebab kematian terbanyak, hingga 30% kasus varisela neonatal. 4,19 Varisela neonatal jenis sindrom varisela fetal memiliki mortalitas hingga 30% pada bulan pertama kehidupan. 7,13 Gambaran klinis jenis ini meliputi berat badan lahir rendah, lesi kulit, abnormalitas okular (katarak, korioretinitis, sindrom Horner), kelainan sistem saraf pusat (kejang, atrofi kortikal), dan hipoplasia anggota gerak.…”

Section: Penularanunclassified

Varisela Neonatal

Prasetya

2020

CDK

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<p>Varisela atau cacar air merupakan infeksi primer virus varicella zoster. Varisela dapat mengenai seluruh kelompok usia termasuk neonatus. Manifestasi klinis pada neonatus tergantung saat paparan. Terdapat tiga jenis varisela neonatal, yakni sindrom varisela fetal, varisela neonatal dini, dan varisela post natal. Diagnosis varisela neonatal terutama ditegakkan secara klinis disertai adanya riwayat paparan. Tatalaksana meliputi rawat inap dan pemberian asiklovir intravena.</p><p>Varicella or chickenpox is a primary varicella zoster virus infection. Varicella infects all age groups including newborns. Clinical manifestations of varicella infection in neonates depend on the time of exposure. Three types of neonatal varicella are fetal varicella syndrome, early neonatal varicella, and post natal varicella. Diagnosis was made mainly by clinical findings and history of exposure. Treatment includes hospitalization and intravenous acyclovir administration.</p>

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Neonatal Varicella Pneumonia: A Rare Presentation

Abstract: Chickenpox is a common infectious disease in children

Cited by 2 publications

References 6 publications

Effects of Intravenous Immunoglobulin and Acyclovir in Preventing Neonatal Varicella

Effects of Intravenous Immunoglobulin and Acyclovir in Preventing Neonatal Varicella

Varisela Neonatal

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