Neonatal Renomegaly

Johnson, Hjalmar W.; Gleave, Martin; Coleman, Gerald U.; Nadel, Helen; Raffel, Joseph; Weckworth, Paul F.

doi:10.1016/s0022-5347(17)43488-4

Cited by 20 publications

(4 citation statements)

References 10 publications

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“…Postnatal follow-up has shown that some hydronephro ses resolve spontaneously [1][2][3] and modem diagnostic tools have disclosed that many cases lack significative obstruction [4], Some never suffer progressive renal de terioration, even in the presence of a significant obstruc tion [4], and autopsies of patients up to the age 80 have exposed clinically unrecognized pelvic dilatations, which were unrelated to the cause of death [5]. These observa tions have led to an intense debate over when to do what.…”

mentioning

confidence: 99%

Suspected Pyelo-Ureteral Junction Obstruction in the Fetus: When to Do What? II. Experimental Viewpoints

Josephson

1991

Eur Urol

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mentioning

confidence: 99%

Suspected Pyelo-Ureteral Junction Obstruction in the Fetus: When to Do What? II. Experimental Viewpoints

Josephson

1991

Eur Urol

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“…Furthermore, the threshold value of the renal pelvis diameter on US to warrant VCUG remains debatable [11,12]. It is well known that prenatal hydronephrosis may represent a transient condition that frequently resolves spontaneously with tubular function maturation, the increasing reabsorption ability, and the ureteropelvic junction maturational process [18,22,24,25,[37][38][39][40]. It has been reported that many children with mild hydronephrosis did not have VUR [6].…”

Section: Discussionmentioning

confidence: 99%

Mild hydronephrosis in newborns and infants: can ultrasound predict the presence of vesicoureteral reflux

et al. 2007

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The objective of our study was to determine the significance of mild hydronephrosis in newborns and infants as an indicator of vesicoureteral reflux (VUR). The voiding cystourethrography (VCUG) of 573 patients aged 0-18 months with mild, sonographically detected hydronephrosis were reviewed for VUR. Patients with secondary reflux or anomalies making an exact reflux grading impossible were excluded. Normal kidneys, contralateral to hydronephrotic ones, were included. Each kidney was considered separately, forming a total of 1,146 renal units. Mild hydronephrosis was defined as an anteroposterior diameter of the renal pelvis of 0.5-1.5 cm without caliectasis. The International Grading System was used to grade VUR. Seven hundred and thirty-six kidneys had mild hydronephrosis. VUR occurred in 189 out of 736 (25.7%) of these kidneys, and in 108 out of 410 (26.3%) non-distended kidneys, contralateral to hydronephrotic ones (p=0.806). No statistical differences in the frequency of VUR and dilatation were found between the subgroups of patients with and without infection, except for a higher grade of reflux in the group with infection. The frequency of VUR in mildly dilated kidneys was not significantly different from that in non-distended ones. There was a poor correlation between VUR and mild hydronephrosis. The latter should not be considered in itself an indication for VCUG in asymptomatic neonates and infants.

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“…The fetal ureter is an example of such a condition [4]. Other explanations for transitional hydronephrosis include decreased diuresis that occurs with growth as tubular function matures, increased absorptive capacity, the increase in the bore of uretero-pelvic junction that probably occurs with growth and possibly to alleviate the harmful effects of any obstructive process [4,5].…”

Section: Discussionmentioning

confidence: 99%