1980
DOI: 10.1542/peds.65.1.57
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Neonatal Renal Failure: Usefulness of Diagnostic Indices

Abstract: Forty-two oliguric neonates were prospectively studied to evaluate the usefulness and reliability of various diagnostic indices in differentiating renal failure from functional (prerenal) oliguria. Twenty-two infants had functional oliguria, 16 had renal failure, and four infants had probable early renal failure. Statistically significant differences between functional oliguria and renal failure were found with regard to the urine sodium, urine to serum ratios of sodium, urea, and creatinine, renal failure ind… Show more

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Cited by 73 publications
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“…It is important to consider these normal patterns for creatinine in assessing the meaning of any particular value, which makes it very difficult to use a single value to diagnose renal failure, except that a clearly elevated value beyond the normal range indicates decreased glomerular function. Often, acute kidney injury (AKI) can be diagnosed by monitoring changes in the creatinine value because during a period of intrinsic renal failure, it usually increases between 0.5 and 1.0 mg/dL (44.2 and 88.4 mcmol/L) per day 3 . Urine output is another key indicator of renal function.…”
mentioning
confidence: 99%
“…It is important to consider these normal patterns for creatinine in assessing the meaning of any particular value, which makes it very difficult to use a single value to diagnose renal failure, except that a clearly elevated value beyond the normal range indicates decreased glomerular function. Often, acute kidney injury (AKI) can be diagnosed by monitoring changes in the creatinine value because during a period of intrinsic renal failure, it usually increases between 0.5 and 1.0 mg/dL (44.2 and 88.4 mcmol/L) per day 3 . Urine output is another key indicator of renal function.…”
mentioning
confidence: 99%
“…It is important to consider these normal patterns for creatinine in assessing the meaning of any particular value, which makes it very difficult to use a single value to diagnose renal failure, except that a clearly elevated value beyond the normal range indicates decreased glomerular function. Often, acute kidney injury (AKI) can be diagnosed by monitoring changes in the creatinine value because during a period of intrinsic renal failure, it usually increases between 0.5 and 1.0 mg/dL (44.2 and 88.4 mcmol/L) per day 3 . Urine output is another key indicator of renal function.…”
mentioning
confidence: 99%