Neonatal purpura due to Neisseria meningitidis serogroup C infection

Katier, Nienke; Traen, Marijke; Dooy, Jozef De; Geyskens, Leentje; Mahieu, Ludo

doi:10.1007/s00431-003-1163-5

Cited by 11 publications

(3 citation statements)

References 6 publications

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“…В одном из исследований материнская вагинальная колонизация была обнаружена в 6 (18,75%) случаях неонатальной МИ [25]. Более того, описаны и клинические примеры ранней неонатальной МИ (с рождения) с доказанной плацентарной инфекцией у матери [30,[50][51][52][53]. Neisseria meningitidis в ряде случаев верифицирована не только культурально, но и с помощью масс-спектрометрии и real-time ПЦР; гистопатологическим исследованием плаценты доказано наличие васкулита сосудов пуповины и хориоамнионита, согласующихся с восходящей инфекцией и воспалительной реакцией матери и ребенка.…”

Section: Discussionunclassified

Generalized Meningococcal Disease in the Newborn: Clinical Case and Literature Review

Izvekova

2023

Pediatr. farmakol.

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Neisseria meningitidis is one of the main etiological factors of meningitis and sepsis in children and adults, however, it is rarely diagnosed in the neonatal period. Clinical definition of neonatal meningococcal disease is complicated, the disease outcome is commonly lethal, and therefore its timely diagnosis and adequate therapy are crucial. This article describes clinical case of the newborn with meningococcal sepsis hospitalized on the 5th day after birth and provides the literature review of the data from the late 19th century until the present.

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Section: Discussionunclassified

Generalized Meningococcal Disease in the Newborn: Clinical Case and Literature Review

Izvekova

2023

Pediatr. farmakol.

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“…We identified 37 previous cases of N. meningitidis meningitis reported in English literature (included our case) between 1916 and 2014 [3][4][5][6][7][8][9][10][11][12][13][14][15][16]. The clinical features, microbiologic results, sero-group outcomes and complications of the 37 cases were summarized in the table (Table 1).…”

Section: Case Reportmentioning

confidence: 99%

“…For the review of previously reported cases [3][4][5][6][7][8][9][10][11][12][13][14][15][16], we defined cases of meningitis associated with N. meningitidis when cases had microbiologic evidence of N. meningitidis consisting of at least one of: a positive culture of blood and/or Cerebrospinal Fluid (CSF) and/or positive Polymerase Chain Reaction (PCR) for meningococcal DNA.…”

Section: Introductionmentioning

confidence: 99%

Meningitis Caused by Neisseria meningitides Serogroup B in a Newborn in China

Wang¹

2016

SOJMID

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SOJ Microbiology & Infectious Diseases Open Access Case Report section at 41 weeks' gestation with a birth weight of 3545g. During pregnancy, his mother was healthy. The natal history was unremarkable. Apgar score was all 10 at 1, 5 and 10 minute. He was breastfed. The neonate was admitted to the hospital due to a one-day history of fever, dispirited, choking, without convulsion, diarrhea or rash. Blood routine: White Blood Cell (WBC) 5.49×10 9 / L, neutrophilic granulocyte 66.1%, lymphocytes 29.3%, hemoglobin, platelets and C-reactive protein (CRP) were normal. X-ray of the chest was unremarkable. No special findings except the total bilirubin, direct and indirect bilirubin were slightly elevated. No exposure to cold patients. On physical Examination: temperature was 38.5°C, weight was 3.48 kilogram, height was 53 centimeters, head circumference was 34 centimeters, respiratory rate was 50 times per minute, heart rate was 182 beats per minute, blood pressure was 84/ 56mmHg. He was conscious and very irritable on handling. Face and trunk were lightly yellow, no rash or petechia. Anterior fontanelle was flat, pupillary reflex was sensitive. The results of cardiovascular and respiratory examinations were normal. The patient did not exhibit organomegaly or eruptions. The capillary filling time was 2 s. Sucking reflex and rooting reflex were normal, grasping and Moro reflex were weak. The blood culture subsequently grew N. meningitidis, and drug sensitive test indicated it was sensitive to Azithromycin,

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