Neonatal Proteus meningoencephalitis

Abstract

Proteus is an uncommon pathogen in neonatal meningitis and has, to our knowledge, not previously been described from Scandinavia. Our case illustrates the typical course of the disease when onset is within the first two weeks of life. The typical patient is a previously healthy, sometimes slightly preterm infant, who develops multiple brain abscesses and has a very poor prognosis. In cases with a later onset, factors predisposing for infection are common and the outcome is less severe. Our patient was a girl born at a gestational age of 36 full weeks, who was a little less alert than normal during the first three days and then became dramatically sick with convulsions and apnoeas. She died at the age of six days with severe brain damage.

Classification, Identification, and Clinical Significance of Proteus, Providencia, and Morganella

“…mirabilis has been implicated in bacteremia (3,106), neonatal meningoencephalitis (39), empyema (49), and osteomyelitis (63). P. penneri has been implicated in a case of bacteremia and concomitant subcutaneous thigh abscess in a neutropenic patient with acute lymphocytic leukemia (23) and in nosocomial urosepsis in a diabetic patient from whom the organism was also subsequently isolated from bronchoalveolar lavage fluid and a pulmonary artery catheter tip (60).…”

Classification, Identification, and Clinical Significance ofProteus,Providencia, andMorganella

“…Their true role, however, remains unsubstantiated. P. mirabilis has been implicated in bacteremia (3,106), neonatal meningoencephalitis (39), empyema (49), and osteomyelitis (63). P. penneri has been implicated in a case of bacteremia and concomitant subcutaneous thigh abscess in a neutropenic patient with acute lymphocytic leukemia (23) and in nosocomial urosepsis in a diabetic patient from whom the organism was also subsequently isolated from bronchoalveolar lavage fluid and a pulmonary artery catheter tip (60).…”

Neonatal Meningoventriculitis Due to Proteus Mirabilis – A Case Report

“…dISCuSSIon P. mirabilis is a ubiquitous saprophytic bacillus and is part of the normal flora of human gastro intestinal tract (GIT). Several cases of bacteremia, meningitis, meningoencephalitis, and cerebral abscess due to P.mirabilis have been reported [2,3,4,5,6].…”