Neonatal Problems

Persson, Bengt; Gentz, J.; Stangenberg, Magnus

doi:10.1007/978-3-642-66972-9_25

Cited by 2 publications

(3 citation statements)

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“…In connection with the amniocentesis, AF volume was determined with the PAH dilution technique (Charles & Jacoby 1966) and samples were taken for analysis of CPR. The newborn infants were observed in a neonatal intensive care unit and neonatal complications were recorded as previously defined (Persson et al 1979).…”

Section: Methodsmentioning

confidence: 99%

“…Radioimmunoassay of C-peptide is not (as is the case with insulin) affected by insulin-binding antibodies of maternal origin. Polyhydramnios is a 0 144-5 786/82/0~OO-0536%02.O0 0 1982 British Journal of Obstetrics and Gynaecology 536 common finding in diabetic pregnancy (Pedersen 1977;Mdlsted-Pedersen 1979) frequently associated with the occurrence of neonatal complications (Persson et al 1979). The only previous study on amniotic fluid C-peptide in diabetic subjects was performed on a selected group which excluded all patients with hydramnios and fetal malformations (Tchobroutsky et al 1980).…”

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confidence: 99%

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Amniotic fluid volumes and concentrations of C‐peptide in diabetic pregnancies

Stangenberg

Persson

Václavínková

1982

BJOG

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Summary. Amniotic fluid (AF) volumes were determined by sodium paminohippurate (PAH) diloution in a consecutive series of 24 diabetic women at 34–35 weeks gestation. AF and maternal venous blood samples were analysed for C‐peptide immunoreactivity (CPR). When the patients were subgrouped according to the presence (n=17) or absence (n=8) of neonatal morbidity, AF volumes (1340±236 ml vs 807±130 ml; mean ±SEM), AF concentrations of CPR (l.38±0.54 nmol/1 vs 0.61±0.14 nmol/1) and maternal blood glucose levels (5.3±0.2 mmol/1 vs 4.8±0.3 mmol/1) during the last trimester of pregnancy were not different. The total content of CPR was significantly (P<0.05) greater in pregnancies with neonatal complications (1.25±0.31 nmol) compared with that in pregnancies without neonatal complications (0.54±0.18 nmol). AF volumes were significantly (P<0.02) larger in pregnancies where feeding problems occurred (1546±307 ml, n=9) compared with that in pregnancies without such problems (957±188 ml,n=16). These findings indicate an impact of fetal hyperinsulinism on the functional maturation of the fetus. When the patients were subgrouped according to the presence or absence of detectable maternal plasma CPR, i.e. >0.05 nmol/1, and to insulin dependent and gestational diabetes no differences of AF volumes, AF concentrations of CPR or total AF contents of CPR were found.

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Amniotic fluid volumes and concentrations of C‐peptide in diabetic pregnancies

Stangenberg

Persson

Václavínková

1982

BJOG

Self Cite

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“…An Apgar score of less than 7 at 1 or 5 min after delivery was consid ered as pathological. The newborn infants were ob served in a neonatal intensive care unit and neonatal complications were recorded as previously defined [ 12]. …”

Section: Methodsmentioning

confidence: 99%

Surveillance of the Diabetic Pregnancy with Antepartum Fetal Nonstress Testing and Urinary Estriol Excretion

Stånge

Stangenberg

Carlström

et al. 1985

Gynecol Obstet Invest

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The value of daily fetal heart rate (FHR) nonstress test (NST) and 24-hour urinary excretion of estriol (E₃) were compared in a consecutive series of 76 diabetic pregnancies. The NST scoring system (0–10 points) employed included monitoring of fetal movements in addition to evaluation of FHR decelerations, accelerations as well as frequency and amplitude of oscillations. Patients were delivered electively after 38 weeks of gestation unless spontaneous labor began earlier or if delivery was indicated for either maternal reasons or presumed fetal distress. Fetal distress was believed to be present if two consecutive NST scores were 6 points or less. Seven patients had a day-to-day E₃ fall of 50% or more at least once. Six of these patients had normal NST scores and 5 of the infants showed no signs of asphyxia at delivery. Forty-two patients had E₃ drops of 30–50% and 27 patients had E₃ drops of less than 30%; in contrast, the NST scores were 6 or less in 15 patients but were normal the next day. These data indicate that measurements of urinary excretion of E₃ give many false alarms of fetal jeopardy and that daily NST can replace measurement of urinary excretion of E₃ and reduce unwarranted intervention and unnecessary prematurity.

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Neonatal Problems

Cited by 2 publications

References 20 publications

Amniotic fluid volumes and concentrations of C‐peptide in diabetic pregnancies

Amniotic fluid volumes and concentrations of C‐peptide in diabetic pregnancies

Surveillance of the Diabetic Pregnancy with Antepartum Fetal Nonstress Testing and Urinary Estriol Excretion

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