Neonatal polycythemia

Krishnan, Lalitha; Rahim, Abdul

doi:10.1007/bf02737765

Cited by 24 publications

(13 citation statements)

References 16 publications

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“…This 1.6% rate is much lower than rates noted in two previous studies. An investigation conducted in India revealed polycythemia in 20.3% of 59 term SGA newborns and 50% of six preterm SGA neonates (Krishnan & Rahim, 1997). The corresponding findings in a report from the Netherlands were 44% of 41 term SGA babies and 35% of 17 preterm SGA babies (De Grauw et al.…”

Section: Discussionmentioning

confidence: 99%

Complete blood count parameters for healthy, small-for-gestational-age, full-term newborns

et al. 2006

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No previous study has investigated the full range of complete blood count (CBC) parameters in small-for-gestational-age (SGA) newborns. The main aim of this study was to compare CBC and peripheral smear parameters in term, healthy SGA neonates and appropriate-for-gestational-age (AGA) neonates, and to establish CBC reference values for full-term SGA newborns. One hundred thirty-two healthy, term newborns (73 SGA and 59 AGA) were included. On day 1, we obtained 109 samples and on day 7 we obtained 77 samples. A CBC and peripheral smear were analyzed for each sample collected and group data were compared. We observed higher mean values for normoblast count, hemoglobin, hematocrit, and red blood cell (RBC) count in the SGA babies than in the AGA babies on day 1. The mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration values for the SGA babies were decreased because of the relatively high RBC count and relatively high mean corpuscular volume we observed in this group. Of the SGA newborns, 21.9% had neutropenia and 4.7% had absolute neutrophil counts lower than 1500/microl on day 1. On both day 1 and day 7, the SGA newborns had higher mean absolute metamyelocyte counts and higher mean I : T (immature : total neutrophil ratio) values than the AGA group. The SGA babies had a lower mean absolute lymphocyte count on day 7 than the AGA group. We detected thrombocytopenia in almost one-third of the 64 SGA newborns tested on day 1. In summary, our study clearly demonstrates that CBC parameters for healthy, full-term, SGA newborns are different from those of healthy, term AGA newborns. This is the first study that has documented different mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, metamyelocyte counts, lymphocyte counts, and I : T in SGA babies compared with AGA babies.

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Section: Discussionmentioning

confidence: 99%

Complete blood count parameters for healthy, small-for-gestational-age, full-term newborns

et al. 2006

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“…Our method can also be viewed as a variation of matching sample techniques where variables of interest across treatment (in our case favorable news group) and control groups (in our case unfavorable news group) are compared. Matching sample techniques have been widely used across different disciplines including psychology, economics, and management science [23,28,30,31].…”

Section: The Portfolio Approachmentioning

confidence: 99%

Do online reviews affect product sales? The role of reviewer characteristics and temporal effects

2008

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Online product reviews provided by consumers who previously purchased products have become a major information source for consumers and marketers regarding product quality. This study extends previous research by conducting a more compelling test of the effect of online reviews on sales. In particular, we consider both quantitative and qualitative aspects of online reviews, such as reviewer quality, reviewer exposure, product coverage, and temporal effects. Using transaction cost economics and uncertainty reduction theories, this study adopts a portfolio approach to assess the effectiveness of the online review market. We show that consumers understand the value difference between favorable news and unfavorable news and respond accordingly. Furthermore, when consumers read online reviews, they pay attention not only to review scores but to other contextual information such as a reviewer's reputation and reviewer exposure. The market responds more favorably to reviews written by reviewers with better reputation and higher exposure. Finally, we demonstrate that the impact of online reviews on sales diminishes over time. This suggests that firms need not provide incentives for customers to write reviews beyond a certain time period after products have been released.

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“…Nineteen of these 25 papers were excluded according to the pre-defined criteria, leaving six randomised trials with a total of 235 newborns that fulfilled the inclusion criteria. [10][11][12][13][14][15] Jan et al did not provide standard deviations for the mean on the post-DET Ht outcome, and as a consequence the results on this outcome cannot be weighted in the metaanalyses. However, these authors did provide information on relief of clinical symptoms and complications of the procedure.…”

Section: Resultsmentioning

confidence: 99%

Systematic review of the optimal fluid for dilutional exchange transfusion in neonatal polycythaemia

Waal¹

2005

Archives of Disease in Childhood - Fetal and Neonatal Edition

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Objectives: Several studies have shown the efficacy of dilutional exchange transfusion (DET) in reducing haematocrit (Ht) and relieving clinical symptoms in neonatal polycythaemia. We conducted a systematic review to determine the efficacy of crystalloid versus colloid solutions used in DET in an effort to identify the best solution to replace red blood cells. Methods: The Cochrane Library, MEDLINE, and EMBASE were searched for relevant randomised controlled trials. Quality assessment and data analysis were performed using the methods and software of the Cochrane Collaboration. Relative risk (RR) and weighted mean difference (WMD) were calculated as measures of effect for categorical and continuous outcome data, respectively. Ninety five percent confidence intervals (95% CI) were calculated and a fixed effect model was used for meta-analysis. Results: Six studies with a total of 235 newborns matched our inclusion criteria. When comparing crystalloid and colloid replacement solutions for DET, there was a clinically unimportant difference in Ht at 2-6 h and at 24 h in favour of colloidal solutions (WMD 2.29% (95% CI 1.28 to 3.31) and 1.74% (95% CI 0.80 to 2.68), respectively). This difference in post DET Ht was more evident when normal saline was compared to plasma but absent when normal saline was compared to 5% albumin. Conclusion: There is little difference in effectiveness between plasma, 5% albumin, and crystalloid solutions. Since normal saline is cheap, readily available, and does not carry the potential risk of transfusion associated infection, normal saline is the optimal dilutional fluid for exchange transfusion in polycythaemic neonates.

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Neonatal polycythemia

Cited by 24 publications

References 16 publications

Complete blood count parameters for healthy, small-for-gestational-age, full-term newborns

Complete blood count parameters for healthy, small-for-gestational-age, full-term newborns

Do online reviews affect product sales? The role of reviewer characteristics and temporal effects

Systematic review of the optimal fluid for dilutional exchange transfusion in neonatal polycythaemia

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