Neonatal pain treatment: ethical to be effective

Bellieni, Carlo V.; Buonocore, Giuseppe

doi:10.1038/sj.jp.7211899

Cited by 14 publications

(9 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Advances in neonatology have significantly improved neonatal morbidity and mortality; but pain, discomfort, and stress remain sad realities for babies in the neonatal intensive care unit [1]. Assessing, managing, and trying to limit these clinical realities, particularly while caring for neonates are challenging and increasingly controversial [2].…”

Section: Introductionmentioning

confidence: 99%

Analgesia for infants’ circumcision

2013

View full text Add to dashboard Cite

Male circumcision (MC) is one of the oldest and most common operations performed all over the world. It can be performed at different ages, using different surgical techniques, for different religious, cultural and medical reasons.Our aim is to examine and compare the various methods of analgesia and different surgical procedures reported in literature that are applied in infant MC. We performed a PubMed, MEDLINE, EMBASE and Cochrane search in the papers published since 2000: 14 studies met the inclusion criteria, most of them showing that a combined pharmacological and non-pharmacological intervention is the best analgesic option, in particular when the dorsal penile nerve block is combined with other treatments. The Mogen surgical procedure seems to be the less painful surgical intervention, when compared with Gomco clamp or PlastiBell device. Only 3 papers studied groups of at least 20 babies each with the use of validated pain scales. Data show a dramatic decrease of pain with dorsal penile nerve block, plus acetaminophen associated to oral sucrose or topic analgesic cream. However, no procedure has been found to definetively eliminate pain; the gold standard procedure to make MC totally painfree has not yet been established.

show abstract

Section: Introductionmentioning

confidence: 99%

Analgesia for infants’ circumcision

2013

View full text Add to dashboard Cite

show abstract

“…Prevention of pain in the newborn is increasingly viewed as a professional imperative and an ethical expectation as untreated pain has detrimental consequences [3,8] including greater pain sensitivity in later childhood[30,33,37,44,55,61]. Newborn experiences with pain may be related to permanent neuroanatomical and behavioral abnormalities as demonstrated in animal models[5,55].…”

Section: Introductionmentioning

confidence: 99%

Warmth is analgesic in healthy newborns

Gray

Lang

Porges

2012

Pain

View full text Add to dashboard Cite

This study identifies a behavioral and nonpharmacologic means of preventing and reducing newborn pain. Our objective was to determine whether warmth is analgesic in newborn infants undergoing vaccination—a routine painful hospital procedure. We used a prospective randomized controlled trial of 47 healthy full-term newborn infants. Infants were randomized into one of three conditions prior to vaccination: warmth exposure, pacifier suckling, or sucrose taste. Crying, grimacing, and heart rate differences were analyzed between groups before, during, and after vaccination as outcome measures. Warmer infants cried significantly less than sucrose taste or pacifier suckling after vaccination. Heart rate patterns reflected this analgesia. Core temperature did not differ between study groups. Providing natural warmth to newborn infants during a painful procedure decreases the crying and grimacing on par with the “gold” standard treatments of sucrose or pacifier.

show abstract

“…The child will say he does not feel well or that he is uncomfortable, that he wants his parents but often he will not rela te this unhappiness to pain." [20] Damals galten Neugeborene zudem als schmerzunempfindlich [4].…”

Section: Schmerzmanagement Bei Kindern In Der Schweizmentioning

confidence: 99%