Neonatal Outcomes from Mothers with Hypertension Disorders of Pregnancy: A Retrospective Study at a Referral Hospital in Rwanda

Abstract

Background
 Globally, maternal hypertensive disorders in pregnancy significantly increase both maternal and perinatal morbidity and mortality. Maternal hypertension affects 14 percent of pregnancies. Eearly detection and management are critical for improving the health outcomes of both mother and neonate.
 Objective
 To assess the association between maternal hypertension disorders in pregnancy and immediate neonatal outcomes at a University Teaching Hospital in Rwanda.
 Methods
 A retrospective study of maternal files with hypertension disorders was conducted from January 1, 2016, to March 31, 2019. A census sample of 114 records and pretested checklist was used to collect data. Descriptive statistics were used to analyze associations between maternal factors and immediate neonatal outcomes.
 Results
 Neonatal outcomes included low birth weight (75.4%), prematurity (59.6%), admission to neonatal intensive care unit (50.4%), intrauterine growth restriction (32.4%), and neonatal death (22.8%). Nearly two-thirds (62%) of mothers had preeclampsia. Significant associations with immediate neonatal outcomes included gestational age, medical history, delivery mode, maternal referral status, preterm birth, prematurity, and abortion.
 Conclusion
 Maternal hypertensive disorders were significantly associated with adverse neonatal outcomes in our study population in Rwanda. Improving early detection, health education, and management of hypertensive disorders in pregnancy is critical to reduce maternal and neonatal morbidity and mortality.
 Rwanda J Med Health Sci 2020;3(2):193-203

Effects of Nifedipine and Labetalol Combined with Magnesium Sulfate on Blood Pressure Control, Blood Coagulation Function, and Maternal and Infant Outcome in Patients with Pregnancy-Induced Hypertension

“…The combined application of labetalol, nifedipine, and magnesium sulfate can effectively improve blood circulation and reduce the damage of hypertension to heart, kidney, and other target organs, thus improving the internal environment [ 33 , 34 ]. It is consistent with the results of Uwizeyimana et al [ 35 ] and Houehanou et al [ 36 ]. Most of the patients with PIH are in hypercoagulable state.…”

Outcome of neonates born to mother with pregnancy induced hypertension: A clinical study

“…Study done byHassan et al, (2015),Uwizeyimana et al, (2020) andGaur et al, (2021) reported that 60%, 50%, 37.8%, 39.7% of neonates respectively suffered from RDS born to mother with PIH. In our study also 9.3% neonates have RDS after the delivery.Most of the surfactant is produced up to 32-34 weeks, but as in neonate born to PIH mother there is more number of preterm delivery therefore most of the neonates have RDS after the delivery.…”