Neonatal Outcome of Infants Born at 500 to 800 Grams From 1990 Through 1998 in a Tertiary Care Center

Abstract

The data document that survival rates continued to improve for 500- to 800-g infants throughout the 1990s. This was concurrent with an increase in "low-risk, expected normal" infants, increased number of deliveries by C/S, decreased incidence of low Apgar scores at both 1 and 5 minutes, and an increased use of antenatal corticosteroids.

Improved Survival Rates With Increased Neurodevelopmental Disability for Extremely Low Birth Weight Infants in the 1990s

“…23 With our definition of neurodevelopmental impairment, for every 100 infants born with birth weights of 500 to 999 g in the 1990s, there were 18 additional survivors, of whom 7 were considered normal and 11 impaired. Improved survival rates similar to ours were reported universally for children with birth weights of Ͻ1000 g. [24][25][26][27] For infants born in the early 1990s, some reported that, despite an increase in survival rates, the neonatal morbidity rates and 20-month neurodevelopmental outcomes were unchanged. 25,[27][28][29][30][31][32] Others reported increased rates of cerebral palsy, neurodevelopmental disabilities, and hearing loss.…”

“…In the later 1990s, during period II, (34) .529 28 (18) 58 (22) .373 42 (20) 106 (26) .129 70-84, no. (%) 14 (28) 25 (18) .299 38 (24) 50 (19) .341 52 (25) 75 (18) .…”

Hospitalizations for critically ill children with traumatic brain injuries: A longitudinal analysis*

“…Recent studies have documented improved outcomes for the treatment of acute myocardial infarction, (5) premature birth (6,7), and hypoplastic left heart syndrome (8). Quantitative evidence is lacking on whether outcomes have improved for a number of different conditions, including traumatic brain injuries involving children.…”

The EPIBEL Study: Outcomes to Discharge From Hospital for Extremely Preterm Infants in Belgium

“…Moreover, most of the previously published outcome data on which health care professionals have to rely for advising parents are based on data for which birth weight (BW) rather than gestational age (GA) served as the basis of comparison, including a significant number of more mature small-for-gestational-age infants with a different outcome profile and thus not useful for prenatal decisions. 2 In addition, most previous reports were not population based, as they examined pooled data over several years of a small number of infants who were treated in different ways. [3][4][5][6][7] The aim of the present study was to examine GAspecific outcomes of a large population-based cohort of infants who were born at Յ26 weeks' gestation and cared for in all 19 perinatal centers of Belgium between January 1999 and December 2000 and to compare the results with those of other geographic GA-based cohorts available in the literature.…”