Abstract:Nicotine is the main psychoactive substance present in cigarette smoke that is transferred to the baby by breast milk. In rats, maternal nicotine exposure during breastfeeding induces obesogenesis and hormone dysfunctions in adult male offspring. As glucocorticoid (GC), insulin, and vitamin D change both adipogenesis and lipogenesis processes, we assessed parameters related to metabolism and action of these hormones in visceral and subcutaneous adipose tissues (VAT and SAT) of adult male and female rats in a m… Show more
“…However, there was no difference in body weight or adiposity between the female offspring. The 180-day-old offspring also exposed to nicotine during lactation, developed obesity and higher visceral fat content [12]. Male (CON 223.1 ± 5.36 bpm vs CIN 259.0 ± 12.7 bpm) and female (CON 211.1 ± 7.2 bpm vs CIN 246.5 ± 7.2 bpm) offspring NIC offspring had a higher heart rate.…”
Nicotine is one of the main psychoactive and toxic substances found in tobacco and itsexposure during the postnatal period can cause several damages to the health of the childduring intrauterine development and in adult life. The aim of this study was to evaluate theeffect of maternal postnatal nicotine exposure on cardiac parameters in adult rat offspring.Weight monitoring, echocardiography and organ collections were performed. In conclusion,offspring from mothers exposed to nicotine develops cardiac hypertrophy, further maleoffspring were more affected.
“…However, there was no difference in body weight or adiposity between the female offspring. The 180-day-old offspring also exposed to nicotine during lactation, developed obesity and higher visceral fat content [12]. Male (CON 223.1 ± 5.36 bpm vs CIN 259.0 ± 12.7 bpm) and female (CON 211.1 ± 7.2 bpm vs CIN 246.5 ± 7.2 bpm) offspring NIC offspring had a higher heart rate.…”
Nicotine is one of the main psychoactive and toxic substances found in tobacco and itsexposure during the postnatal period can cause several damages to the health of the childduring intrauterine development and in adult life. The aim of this study was to evaluate theeffect of maternal postnatal nicotine exposure on cardiac parameters in adult rat offspring.Weight monitoring, echocardiography and organ collections were performed. In conclusion,offspring from mothers exposed to nicotine develops cardiac hypertrophy, further maleoffspring were more affected.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.