Neonatal nevus lipomatosus cutaneous superficialis managed by surgical resection alone

Abstract

Nevus lipomatosus cutaneous superficialis (NLCS) is a rare, benign hamartomatous lesion characterized histologically by the presence of ectopic adipocytes in the dermis. This condition was first reported in 1921 in a German journal for dermatologic and venereal diseases. 1 Such lesions are often reported classically as Hoffman-Zurhelle lesions-the namesake of its founders. They are described as multiple, pedunculated lesions presenting en masse. The other, rarer clinical variant, is characterized by a singular rounded papule with no stalk. 2 Hoffman-Zurhelle NLCS can present at birth or in the first 3 decades of life, whereas the solitary variant appears typically after the second decade of adult life. 2 They are uncommonly seen with a necrotic or ulcerating appearance. In this report, we describe a unique case of a torted and infarcted NLCS found in the intergluteal cleft of an 18-hour-old female neonate. | CASE PRESENTATIONA Gravida 4 Para 2 Caucasian lady was referred to the Maternal Fetal Medicine service at our center-a tertiary children's hospital-for an abnormal "soft tissue mass" discovered in her third-trimester antenatal ultrasound. Geographically, she lived >4 hours away and was receiving

Nevus Lipomatosus Superficialis in a Serous Inflammatory Capsule: A Case Report

“…Given that the patient endorsed friction rubbing at the lesion site with walking, the inflammatory process was likely due to torsion of the lesion. One previously reported case of inflamed and necrosed NLS in a neonate reported similar histological findings and had also attributed the presentation to torsion of the lesion [ 6 ].…”

Ultrasonographic findings in nevus lipomatosus cutaneous superficialis: What differentiates this tumor from other soft tissue tumors?

“…Due to the small sample size, these eight cases have not covered NLCS's potential features, particularly those complicated by inflammation. An inflammatory process following lesion torsion may result in different NLCS features, such as an acute enlargement of the lesion and serous fluid collection around the lesion, as well as separation of the epidermis from the dermis layer 18,19 . Moreover, in this study, we did not perform elastography, which is used to assess the stiffness or elasticity of various tumors.…”

“…An inflammatory process following lesion torsion may result in different NLCS features, such as an acute enlargement of the lesion and serous fluid collection around the lesion, as well as separation of the epidermis from the dermis layer. 18,19 Moreover, in this study, we did not perform elastography, which is used to assess the stiffness or elasticity of various tumors. Therefore, to establish the ultrasound characteristic of NLCS, it would be useful to accumulate more cases, including those with inflammation, as well as data from analyses using various techniques, such as elastography.…”