Neonatal neurobehavioral tests following cesarean section under general and spinal anesthesia

Hodgkinson, Robert; Bhatt, M.; Kim, S.S.; Grewal, G.; Marx, Gertie F.

doi:10.1016/0002-9378(78)90862-1

Cited by 52 publications

(14 citation statements)

References 11 publications

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“…17 Neonatal outcome can be assessed by Apgar scores, which is a good index of immediate survival. 18 Unfortunately it does not correlate well with transient intrapartum events or later neurological damage. We demonstrated no difference in the Apgar scores between groups at one and five minutes.…”

Section: Discussionmentioning

confidence: 99%

Is ephedrine infusion more effective at preventing hypotension than traditional prehydration during spinal anaesthesia for caesarean section in African parturients?

Desalu

Kushimo

2005

International Journal of Obstetric Anesthesia

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Section: Discussionmentioning

confidence: 99%

Is ephedrine infusion more effective at preventing hypotension than traditional prehydration during spinal anaesthesia for caesarean section in African parturients?

Desalu

Kushimo

2005

International Journal of Obstetric Anesthesia

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“…There was a lower incidence of maternal awareness after ketamine compared with thiopental and the incidence of dysphoric reactions or hallucinations was low (Baraka et al 1989;Schultetus et al 1986). Neonatal neurobehavioural scores were also satisfactory (Hodgkinson et al 1978). Ketamine may increase uterine tone and concerns about dysphoric reactions remain.…”

Section: Ketaminementioning

confidence: 94%

“…Thiopental 3 to 5 mg/kg is used commonly but neonatal neurobehavioural test scores after caesarean section are lower than those after regional anaesthesia (Hodgkinson et al 1978). Induction of anaesthesia with thiopental 4 mg/kg also reduced intervillous blood flow by 35% (Jouppilla et al 1979).…”

Section: Thiopentalmentioning

confidence: 98%

Pharmacokinetic Optimisation of General Anaesthesia in Pregnancy

Gin

1993

Clinical Pharmacokinetics

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A significant proportion of women require general anaesthesia during pregnancy or for delivery. There are many practical difficulties in studying anaesthetic drugs and techniques to determine what may be best for both the mother and fetus. Physiological changes of pregnancy may alter the pharmacokinetics and pharmacodynamics of anaesthetics and the fetal disposition of drugs is largely unknown. With the limited pharmacokinetic data available, conclusions on the suitability of drugs are reached in conjunction with sophisticated neonatal neurobehavioural testing. The normal fetus appears able to withstand a variety of anaesthetic techniques but there is little information regarding the compromised fetus or premature neonate. Provided that adequate maternal anaesthesia is achieved, it is prudent to choose an anaesthetic technique which minimises fetal exposure to drugs and use agents which can be eliminated quickly by the neonate. Currently available drugs with rapid maternal and neonatal elimination include propofol, suxamethonium, atracurium, nitrous oxide and isoflurane.

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“…Spinal anaesthesia was associated with better neurobehavioral assessment as evidenced by higher ENNS scores. 13 Corke, Datta and Ostheimer in 1982 pro-spectively examined acid-base values and performed neonatal neurobehavioral studies in babies born to mothers who had received spinal anaesthesia for Caesarean section. Although the babies born to mothers who had sustained hypotension were more acidotic than controls, no neurobehavioral abnormalities were noted at 4 and 24 hr of life.…”

Section: Fetal Effectsmentioning

confidence: 99%

Spinal anaesthesia in obstetrics

Morgan

1995

Can J Anaesth

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Spinal anaesthesia has been used since the 1800s but, due to a number of complications, the popularity of this technique has waxed and waned. In the 1950s, it was the most widely used method of anaesthesia and analgesia in obstetrics but it fell out of fashion with the arrival of the epidural technique which allowed a continuous method of delivering analgesia with relatively few complications. Hypotension and the high incidence of postdural puncture headaches were two reasons for the decline in the popularity of spinal anaesthesia in the young, otherwise healthy pregnant population. With the development of newer needles and bevel designs and methods whereby the incidence of hypotension can be minimized, spinal anaesthesia is making a reappearance in obstetrical anaesthesia spheres. The purpose of this article is to review the history, effects, technique, indications, contraindications and complications of this method of anesthesia as it applies to the obstetrical patient.

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Neonatal neurobehavioral tests following cesarean section under general and spinal anesthesia

Cited by 52 publications

References 11 publications

Is ephedrine infusion more effective at preventing hypotension than traditional prehydration during spinal anaesthesia for caesarean section in African parturients?

Is ephedrine infusion more effective at preventing hypotension than traditional prehydration during spinal anaesthesia for caesarean section in African parturients?

Pharmacokinetic Optimisation of General Anaesthesia in Pregnancy

Spinal anaesthesia in obstetrics

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