Neonatal mortality: the chance for improvement

Gadzinowski, Janusz

doi:10.1038/jp.2008.24

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“…2008.126 Thanks to Dr Garg and Dr Gogia for their letter in regard to my Editorial in Journal of Perinatology of May 2008. 1 They bring an important point of view in relation to priorities of developing world. We wish to clarify our views.…”

Section: Response To Dr Garg and Dr Gogiamentioning

confidence: 99%

Response to Dr Garg and Dr Gogia

Gadzinowski

2008

J Perinatol

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Section: Response To Dr Garg and Dr Gogiamentioning

confidence: 99%

Response to Dr Garg and Dr Gogia

Gadzinowski

2008

J Perinatol

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Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome

Abdellatif

Davis

Wheeler

et al. 2021

Cochrane Database of Systematic Reviews

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Reducing neonatal mortality in developing countries: low-cost interventions are the key determinants

Garg

Gogia

2008

J Perinatol

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did not reduce all-cause mortality. When compared with infants receiving the animal-derived surfactants beractant and poractant alfa, infants receiving lucinactant were found to have similar rates of mortality and morbidity from respiratory distress syndrome. More analysis is needed before the findings from lucinactant studies can be generalized because of questions about early trial closure and limited statistical power. Moreover, the metabolic fate of lucinactant and its component chemicals and potential risks introduced by the requirement to convert the lucinactant gel into a liquid using a special warming cradle immediately before instillation need additional study '. 3 So that takes us back to where we started with the 'warming cradle' rather than the 'water bath'.Finally, I agree with the American Academy of Pediatrics when it says 'new synthetic surfactants with surfactant protein-like activity are promising new treatments for surfactant-deficiency disorders' 3 and I hope that such a product is approved for treatment of RDS in the United States and Europe in the near future.

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Neonatal mortality: the chance for improvement

Cited by 3 publications

References 19 publications

Response to Dr Garg and Dr Gogia

Response to Dr Garg and Dr Gogia

Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome

Reducing neonatal mortality in developing countries: low-cost interventions are the key determinants

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