Neonatal mortality—4 million reasons for progress

Thea, Donald M.; Qazi, Shamim

doi:10.1016/s0140-6736(08)60810-7

Cited by 11 publications

(3 citation statements)

References 7 publications

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“…The NMR of rural China is also much lower than the global NMR (20‰) and many middle income and developing countries, such as Brazil (9.1‰) and India (28.1‰) (1). It is impossible to achieve MGD4 without substantial reductions in early neonatal mortality (7). Estimates indicate that global ENMR was reduced by 37.6%, which was much lower than late neonatal mortality rate (52.7%) from 1990 to 2013 (1).…”

Section: Discussionmentioning

confidence: 99%

Neonatal mortality in the urban and rural China between 1996 and 2013: a retrospective study

Guo³

et al. 2016

Pediatr Res

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Section: Discussionmentioning

confidence: 99%

Neonatal mortality in the urban and rural China between 1996 and 2013: a retrospective study

Guo³

et al. 2016

Pediatr Res

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“…The perinatal period represents the first window of potential antibiotic exposure in humans. This period is characterized by a high incidence of neonatal infections, which are the leading cause of death ( Thea and Qazi, 2008 ), and corresponds to an increased risk of exposure to nosocomial infection in hospitalized newborns. During this period, the absence of markers or symptoms suggestive of infection makes it difficult to establish a diagnosis, resulting in an early and probabilistic prescription.…”

Section: Antibioticsmentioning

confidence: 99%

First 1000 Days of Life: Consequences of Antibiotics on Gut Microbiota

Aires

2021

Front. Microbiol.

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The developmental origin of health and disease highlights the importance of the period of the first 1000 days (from conception to 2 years) of life. In particular, the process of gut microbiota establishment occurs within this time window. Therefore, determinants interfering with neonatal gut establishment may disrupt its physiological functions and potentially lead to negative health outcomes. Antibiotics are among perinatal determinants that can directly or indirectly affect the pattern of gut bacterial colonization, with a long-lasting impact on intestinal ecosystem functions. In this review, we will examine the impact of antibiotics on the intestinal microbiota during the perinatal period and first years of life, a key interval for development of an individual’s health capital. Further, we will discuss the role of antibiotics during short- and long-term dysbiosis and their associated health consequences.

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“…This is important because patients often delay seeking care, even in cases severe illness [37], and scheduled visits have been shown to be part of effective interventions [5]. Prior research has shown that using CHWs as part of a comprehensive public health delivery strategy can positively change behavior and significantly lower mortality rates [5,19,31], particularly for maternal and newborn health.…”

Section: Background and Related Workmentioning

confidence: 99%

Closing the Feedback Loop

DeRenzi

Wacksman

Dell

et al. 2016

Proceedings of the Eighth International Conference on Information and Communication Technologies and Development

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Accredited Social Health Activists (ASHAs) have been shown to have a positive impact on health outcomes of the households they visit, particularly in maternal and neonatal health. As the first line of the public health system in many countries, they are a critical link to the broader public health infrastructure for community members. Yet they do this all with minimal training and limited support infrastructure. To a pregnant woman, an ASHA is a trusted ally in navigating the health system-information gathered is returned by appropriate advice and counseling. To the health system, the ASHA is a key channel of valuable householdlevel information for the public health system, yet she generally receives minimal guidance in return. In this paper we present ASTA-the ASHA Self-Tracking Application-a system that provides ASHAs with timely, on-demand information regarding their own performance compared to their peers. Using ASTA, ASHAs access comparative performance data through both a web-based and voice-based interface on demand. We evaluated ASTA through a 12-month deployment with 142 ASHAs in Uttar Pradesh, India, assessing the impact of providing feedback on ASHA performance. We find that ASHAs with access to the ASTA system made significantly more client visits, with average monthly visits 21.5% higher than ASHAs who had access to a control system. In addition, higher ASHA performance was correlated with increased usage of ASTA. However, the performance improvement was front-loaded, with the impact of the system decreasing toward the end of the study period. Taken together, our findings provide promising evidence that studying and incorporating tools like ASTA could be cost effective and impactful for ASHA programs.

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Neonatal mortality—4 million reasons for progress

Cited by 11 publications

References 7 publications

Neonatal mortality in the urban and rural China between 1996 and 2013: a retrospective study

Neonatal mortality in the urban and rural China between 1996 and 2013: a retrospective study

First 1000 Days of Life: Consequences of Antibiotics on Gut Microbiota

Closing the Feedback Loop

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