Neonatal Mechanical Ventilation-Early Experiences in central India

Dutt, Rajdhar; Dutt, Chandrakala; Ambey, Ravi

doi:10.17511/ijmrr.2014.i04.10

Cited by 5 publications

(13 citation statements)

References 7 publications

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“…[ 6 ] In the present study, the most ventilated babies were 0f 1000–1499 g (18%) while the mean birth weight in survived neonates was 2173 ± 665 g and expired neonates was 1611 ± 792 g. Trivedi et al .,[ 7 ] Hossain et al .,[ 5 ] and Dutt et al . [ 2 ] also reported higher survival in babies weighing >2000 g: 56.7%, 52.1%, and 51%, respectively, as in our study, it was 52.6%. The intrauterine growth showed statistical significance ( P < 0.01) showing that AGA babies had the highest survival rate (54.5%) and mortality was least in LGA babies.…”

Section: Discussionsupporting

confidence: 85%

“…Dutt et al . [ 2 ] found it as the third-most common (18.98%) while Mathur et al . [ 3 ] as fourth-most common cause (8.4%) of ventilation.…”

Section: Discussionmentioning

confidence: 99%

“…The severely asphyxiated babies (APGAR 0–3 at 5 min) has the poorest survival of 10% ( P = 0.03). Similar to Trivedi et al .,[ 7 ] (20%) whereas higher survival rate seen by Dutt et al .,[ 2 ] (40%) and Nayana et al .,[ 4 ] (100%).…”

Section: Discussionmentioning

confidence: 99%

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Clinicoetiological pattern and outcome of neonates requiring mechanical ventilation: Study in a tertiary care centre

Yadav

Chauhan

Bhardwaj

et al. 2018

Indian Journal of Critical Care Medicine

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The clinical and etiological pattern of ventilated newborns, their outcome in relation to morbidity and mortality was studied with 50 ventilated newborns, including outborns. M:f ratio was 2.1:1. The most common gestational age 28–36 weeks (60%) and mostly were appropriate for gestational age (66%). Survival rate 40% (20/50) being directly proportional to the gestational age and intrauterine growth pattern (P < 0.01). Babies by LSCS Lower Segment Cessarian Section survived more than born by normal vaginal delivery (46.7% vs. 37.1%). More outborn survival could be related to their advanced gestational age on presentation. The initial assessment of APGAR score of >7 had a better outcome (56.3%; P < 0.03). The most common indication of ventilation was hyaline membrane disease (19/50) but the survival rate best in babies with meconium aspiration syndrome (54.5%). The most prevalent complication was sepsis (survival rate 60%) while conditions such as shock, intraventricular hemorrhage, disseminated intravascular coagulation, air leak syndrome, and pulmonary hemorrhage had 100% mortality. Thus, the outcome as survival is constrained by many factors; newborn's profile, conditions at birth, and postnatal resuscitation.

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Section: Discussionsupporting

confidence: 85%

“…Dutt et al . [ 2 ] found it as the third-most common (18.98%) while Mathur et al . [ 3 ] as fourth-most common cause (8.4%) of ventilation.…”

Section: Discussionmentioning

confidence: 99%

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Clinicoetiological pattern and outcome of neonates requiring mechanical ventilation: Study in a tertiary care centre

Yadav

Chauhan

Bhardwaj

et al. 2018

Indian Journal of Critical Care Medicine

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“…Other Indian studies reported a similar cohort with 16 to 17% for < 32 weeks gestation, 30% to 40% for 32 to 37 respectively. 10,11 Preterm babies suffer from RDS, apnea, sepsis, pneumonia, pulmonary haemorrhage etc. and they need mechanical ventilation more than term neonates.…”

Section: Discussionmentioning

confidence: 99%

Clinical Profile, Outcome and Risk Factors for Mortality of Neonates Requiring Mechanical Ventilation at Tertiary Care Centre of Central Gujarat, India

Thakkar¹,

Pansuriya²,

Bharani³

et al. 2021

J. Nepal Paedtr. Soc.

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Introduction: Mechanical ventilation is an important factor contributing to the reduced neonatal mortality in NICU. However, many ventilated babies are left with detrimental sequelae. This study was undertaken to know the prognostic predictors and survival outcome in the ventilated neonates. We assessed the clinical profile, outcome of mechanical ventilation and analysed the risk factors for mortality and complications resulting from mechanical ventilation. Methods: A prospective study was conducted at the NICU of a tertiary care hospital in India. The study period was from May 2015 to April 2016. Neonates who underwent mechanical ventilation and met the inclusion criteria were enrolled in the study. Their demographic profile, outcomes and risk factors were documented and analysed using appropriate statistical methods. Results: 285 neonates required mechanical ventilation during the study period. Among them, 190 were included in the study. Overall mortality was 99 out of the 190 enrolled (52%). The most common indications for mechanical ventilation were Respiratory Distress Syndrome (RDS), Meconium Aspiration Syndrome (MAS) and apnea. Risk factors contributing significantly to higher mortality of ventilated neonates were very low birth weight (VLBW), gestation of less than 32 weeks, shock, ventilator- associated complications like pneumothorax and pulmonary haemorrhage. In multiple regression analysis, very low birth weight, circulatory disturbances, pneumothorax, pulmonary haemorrhage, and higher initial FiO2 requirement were found to be independent risk factors of mortality. Conclusions: The commonest indications for mechanical ventilation were RDS and MAS. Significantly higher mortality was seen amongst VLBW, preterm neonates. Co-morbidities like circulatory disturbance, and complications like pneumothorax and pulmonary haemorrhage contributed to adverse outcomes.

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“…MV (Mechanical Ventilation) was introduced in the West in 1960s to support the infants with respiratory failure 11 . This innovative technology have reached to significant level in affluent nation, but due to its high cost, expert skill requirements has limited its use in developing countries 12 . Bangladesh is a developing country.…”

Section: Original Articlementioning

confidence: 99%

Immediate Outcome of Mechanically Ventilated Neonate : One Year Experience in Neonatal Intensive Care Unit of Combined Military Hospital Dhaka

et al. 2022

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Background: A large number of neonates in intensive care unit require mechanical ventilation due to various disease conditions. There has been a dramatic fall in neonatal mortality in developed countries with the advent of mechanical ventilation. This study was carried out to see the immediate outcome of neonates who required mechanical ventilation. Materials and methods: This prospective observational study was carried out in Neonatal Intensive Care Unit, CMH Dhaka from January 2016 to December 2016. Neonates who required mechanical ventilation during the study period were enrolled in this study. During the time of mechanical ventilation neonates were followed up for any complication till discharge or death. Results: Total 30 neonates were enrolled in the study. Among them 22(73.3%) of the neonates were preterm and 8(26.7%) were term, 25(83.3%) having birth weight <2500 gm. Respiratory Distress Syndrome was the most common reason for mechanical ventilation accounting for 11(36.7%),other indications were Perinatal Asphyxia 7(23.3%), Septicemia 6(20.0%), Congenital Pneumonia 5(16.7%) and Meconium Aspiration Syndrome 1(3.3%). Common complications during the period of ventilation were Septicemia (40.0%), Acute Renal Failure (16.7%), Pneumonia (16.7%), Pulmonary Hemorrhage (10.0%), Intraventricular Hemorrhage (6.7%), Pneumothorax(10.0%) and Heart Failure (6.7%). 17(56.7%) neonates survived and 13(43.3%) were died. Most of the neonate died of Perinatal Asphyxia 4(57.1%), Septicemia 3(50.0%), RDS 5(45.5%) and Congenital Pneumonia 1(20.0%). Conclusion: The survival rate of ventilated neonates was 56.7%. The higher gestational age and birth weight was significantly associated with better outcome. Septicemia and Pneumonia (PNA) was the leading cause of death in this study. Effective measures for prevention and management of sepsis could improve the outcome of neonates in NICU. IAHS Medical Journal Vol 4(2), June 2021; 27-32

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Neonatal Mechanical Ventilation-Early Experiences in central India

Cited by 5 publications

References 7 publications

Clinicoetiological pattern and outcome of neonates requiring mechanical ventilation: Study in a tertiary care centre

Clinicoetiological pattern and outcome of neonates requiring mechanical ventilation: Study in a tertiary care centre

Clinical Profile, Outcome and Risk Factors for Mortality of Neonates Requiring Mechanical Ventilation at Tertiary Care Centre of Central Gujarat, India

Immediate Outcome of Mechanically Ventilated Neonate : One Year Experience in Neonatal Intensive Care Unit of Combined Military Hospital Dhaka

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