Neonatal jaundice in Asia

Ho, Nai Kiong

doi:10.1016/s0950-3536(11)80038-7

Cited by 37 publications

(25 citation statements)

References 25 publications

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“…A prospective study conducted in a neonatal unit in Karachi admitted 414 neonates with jaundice and identified kernicterus in 11.4% of the neonates (Arif 1982). Neonatal jaundice is recognized as a major problem in other Asian countries as well (Ho 1992). However, large‐scale prospective studies documenting incidence of jaundice have not been reported from any part of the world (Newman et al.…”

Section: Introductionmentioning

confidence: 99%

Incidence of neonatal hyperbilirubinemia: a population-based prospective study in Pakistan

Tikmani

Warraich

Abbasi

et al. 2010

Tropical Medicine &Amp; International Health

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Summaryobjective To estimate the incidence of neonatal jaundice and hyperbilirubinemia in a poor urban community in Karachi, where 70% of births occur at home.methods Home-based pregnancy and newborn surveillance were conducted from September 2004 to July 2006 in a multi-ethnic population by trained community health workers. Newborns were visited several times at scheduled intervals until 59 days of life; any baby with jaundice was referred to the local clinic. Clinical assessments of jaundice were assigned by a physician and recorded using an adapted Kramer scale. Blood for plasma bilirubin was obtained if parents consented.results Of a birth cohort of 1690 young infants during the study period, 466 infants (27.6%) were referred to our centre with jaundice. Of these, 64% were 0-6 days old. Bilirubin was measured in 125 of 466 (27%) jaundiced newborns. Overall detected rate of hyperbilirubinemia (bilirubin >5 mg ⁄ dl) among 1690 newborns was 39.7 ⁄ 1000 live births (95% CI 29.3-47.6). Rate of plasma bilirubin levels in the range of 15-20 mg ⁄ dl was 13 ⁄ 1000 live births (95% CI 7.6-18.4); levels >20 mg ⁄ dl were observed in 3.5 ⁄ 1000 live births (95% CI 0.4-5.5). The proportion of newborns with bilirubin ‡15 mg ⁄ dl was significantly higher among those assigned a Kramer score of 4-5 compared to those receiving a score of 1-3 (P-value 0.00004).conclusion A significant burden of untreated severe neonatal jaundice, causing potential neurological sequelae, exists in developing countries such as Pakistan. WHO guidelines are needed for screening and appropriate management of neonatal jaundice in developing countries.

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Section: Introductionmentioning

confidence: 99%

Incidence of neonatal hyperbilirubinemia: a population-based prospective study in Pakistan

Tikmani

Warraich

Abbasi

et al. 2010

Tropical Medicine &Amp; International Health

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“…Many authors have unable to establish the etiology of hyperbilirubinemia in more than half of the cases in their series (12) . Prematurity is an important cause of neonatal hyperbilirubinemia and has been well documented in the literature (13,14,15) . In our study too as many as 18% of the cases were due to prematurity.…”

Section: Jmscr Vol||05||issue||09||page 27371-27377||septembermentioning

confidence: 99%

Clinical and Biochemical Profile of Neonates with Hyperbilirubinemia in a Tertiary Care Center

Chhetri¹

2017

jmscr

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“…Newborns of Asian heritage commonly develop hyperbilirubinaemia at birth and are at increased risk of bilirubinrelated encephalopathy. [1][2][3] Early detection and diagnosis are essential in order to initiate treatment before neurologic impairment and disability ensue. In developing countries lacking routine screening protocols, significant jaundice is often missed.…”

Section: What This Paper Addsmentioning

confidence: 99%

Home‐use icterometry in neonatal hyperbilirubinaemia: Cluster‐randomised controlled trial in Vietnam

Luu

Tran

et al. 2014

J Paediatrics Child Health

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Neonatal jaundice in Asia

Cited by 37 publications

References 25 publications

Incidence of neonatal hyperbilirubinemia: a population-based prospective study in Pakistan

Incidence of neonatal hyperbilirubinemia: a population-based prospective study in Pakistan

Clinical and Biochemical Profile of Neonates with Hyperbilirubinemia in a Tertiary Care Center

Home‐use icterometry in neonatal hyperbilirubinaemia: Cluster‐randomised controlled trial in Vietnam

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