Neonatal hypoglycaemia: prevalence and clinical manifestations in Port Harcourt, Nigeria

Frank-Briggs, AI; Ojule, AC; Nkanginieme, K E O

doi:10.4314/phmedj.v2i2.38916

Cited by 7 publications

(15 citation statements)

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“…The prevalence of neonatal hypoglycaemia in the present study was 11.0 percent, much lower than the 28.3 percent reported from Port Harcourt by Frank-Briggs [4] and 32.7 percent by Dedeke et al [5]. This is comparable to 9.5 percent reported by Njokanma and Fagbule [12] and 6.6 percent by Omene in Benin [13].…”

Section: Discussioncontrasting

confidence: 46%

“…If this approach fails, intravenous therapy should be instituted when facilities are available. Studies have been done on neonatal hypoglycaemia in other parts of Nigeria [4] [5], but there has been no previous documentation on the prevalence of neonatal hypoglycaemia at Benue State University Teaching Hospital, Makurdi, Benue State. The present study was therefore undertaken to determine the prevalence of hypoglycaemia in the newborn, and the associated maternal/neonatal risk factors.…”

Section: Introductionmentioning

confidence: 99%

“…It is defined either as whole blood glucose of less than 2.2 mmol/L or plasma glucose of less than or equal to 2.5 mmol/L [2]. Neonatal hypoglycaemia affects 5% to 15% of otherwise healthy babies [2] [3] and is widespread in resource poor countries [4] [5]. About 8% of large for gestational age infants and 15% of preterm infants and infants who have intrauterine growth retardation (IUGR) have been reported as having hypoglycaemia.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of Hypoglycaemia in Newborn at Benue State University Teaching Hospital, Makurdi, Benue State, Nigeria

Ochoga¹,

Michael²,

Abah³

et al. 2018

OJPed

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Background: Neonatal hypoglycaemia is the most common metabolic abnormality in neonates and is associated with neurological damage and death when it occurs during the first few days of life. The main objective of this study was to determine the prevalence of hypoglycaemia in the newborn and the associated maternal/neonatal risk factors. Setting and Methods: This prospective descriptive study was conducted at the labour room and the Special Care Baby Unit of Benue State University Teaching Hospital, Makurdi, Benue State, Nigeria, between July 2017-March 2018. Results: Of the 168 neonates, 140 (83.3%) were delivered in the hospital and 28 (16.7%) were delivered outside the hospital. Hypoglycaemia was found in 19 (11.0%) of the neonates. The mean (standard deviation) of gestational age was 37.8 (3.0) weeks. 91 (54.2%) were males and 77 (45.8%) were females. Male to female ratio is 1.2:1. A significantly higher proportion of 9 (32.1%) out born compared with 10 (7.1%) of inborn, 4 (44.4%) of birth < 1500 g compared with 5 (22.7%) birth weight 1500 g -2499 g and 10 (7.3%) of birth weight ≥ 2500 g and 7 (22.6%) of babies with temperature ≤ 36.5˚C compared with 7 (6.3%) of temperature 36.5˚C -37.5˚C and 5 (19.2%) of temperature > 37.5˚C, demonstrated hypoglycaemia respectively. Neonatal risk factors, such as, prematurity, low birth weight and respiratory distress syndrome, were significantly associated with hypoglycaemia p-value of 0.02, 0.01 and 0.00 respectively. There were no statistically significant associations between maternal risk factors and hypoglycaemia. The common presenting symptoms were jitteriness, cyanosis, tachypnoea, hypotonia, apnoea, temperature instability, seizure and lethargy. Conclusion: The prevalence of hypoglycaemia was 11.0% in the present

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Section: Discussioncontrasting

confidence: 46%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prevalence of Hypoglycaemia in Newborn at Benue State University Teaching Hospital, Makurdi, Benue State, Nigeria

Ochoga¹,

Michael²,

Abah³

et al. 2018

OJPed

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“…As there are few reports on neonatal hypoglycaemia in developing countries like Ethiopia [14][15][16][17][18], we evaluated transient neonatal hypoglycaemia which is seen in the rst 48 hours [22] and its association with maternal, obstetric and neonatal factors in a tertiary care hospital setting from a developing country. In this study we found prevalence of hypoglycaemia in 25% of the neonates.…”

Section: Discussionmentioning

confidence: 99%

“…Reports on prevalence and risk factors of neonatal hypoglycaemia in developing countries in general [14][15][16][17] and in Ethiopia in particular are limited [18]. Since Ethiopia has one of the highest neonatal mortality rates, decreasing preventable neonatal death is an essential public health concern [19].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk factors of Hypoglycaemia in Neonates at St. Paul’s Hospital Millennium Medical College Neonatal Intensive Care Unit, Ethiopia: A Cross Sectional Study

Fantahun¹,

Nurussen²

2020

Preprint

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Background Hypoglycaemia is a common metabolic abnormality seen in neonates that can cause preventable death. Its overall incidence has been estimated to be 1 to 5 per 1,000 live births, with higher incidence in at-risk populations. There is limited data regarding its prevalence and risk factors in developing countries like Ethiopia. Therefore, this study was aimed to determine the prevalence and risk factors of neonatal hypoglycaemia in neonatal intensive care unit (NICU) at Saint Paul’s Hospital Millennium Medical College (SPHMMC), Addis Ababa, Ethiopia. Methodology A cross sectional study was conducted from June 17 to August 3, 2018 at SPHMMC, NICU. Neonates whose age was less than 48hrs and admitted to NICU were enrolled. Sociodemographic, maternal and neonatal factors were collected using structured questionnaire. Blood glucose was measured using glucometer with a test strip. Random blood glucose level < 47mg/dl was taken as a cut-off point to define hypoglycaemia. The data was entered and analysed using SPSS version 20. Results Neonatal hypoglycaemia was detected in 25% (49/196) of the neonates. Birth weight, duration of labor, maternal age, time of feeding initiation, hypothermia and respiratory distress syndrome were associated with hypoglycaemia. From these factors, maternal age, birth weight and hypothermia were found to be independent predictors of the outcome. Conclusion Hypoglycaemia was prevalent in neonates admitted to the NICU of SPHMMC and was associated with low birth weight and hypothermia. These findings calls for early detection of hypoglycaemia, prevention of hypothermia and early initiation of feeding to prevent neonatal morbidity and mortality.

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Maximizing the detection rate of hypoglycemia among preterm neonates admitted in Neonatal intensive care unit in Ethiopia, 2021

Chanie

Shiferaw

Feleke

et al. 2023

Sci Rep

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The burden of hypoglycemia is high in resource limited countries, such as Ethiopia. However, there are no sufficient studies conducted in Ethiopia in general and in the study setting in particular in the previous era. Hence, this study aims to assess the proportion of hypoglycemia and associated factors among preterm neonates admitted to the neonatal intensive care unit at Debre Tabor Comprehensive Specialized Hospital, Ethiopia, in 2021. A hospital-based cross-sectional study was conducted from October 1 to December 30, 2021, at Debre Tabor Comprehensive Specialized Hospital in the neonatal intensive care unit ward. The data was entered in Epi-info 7 and exported to STATA version 14. A binary and multivariable logistic regression was computed at 95% confidence interval (CI). During bivariable analysis, variables having a p-value of less than 0.25 were chosen for multivariable logistic regression analysis, and variables having a p-value of less than 0.05 in multivariable analysis, were significant associations with the dependent variable. The study included 267 preterm neonates, and 23.59% (95% CI 18.9–29.1) were develop hypoglycemia. Moreover, 49 (18.35%) preterm neonates died during the study period. In this study, preterm neonates with hypothermia [Adjusted Odds Ratio (AOR = 4.5; 95 CI 3.4, 7.2)], birth asphyxia (AOR = 5.1; 95 CI 3.9, 27.1), seizure (AOR = 4.7; 95 CI 2.8, 17.8), and also preterm neonates born from diabetic mothers (AOR = 6.7; 95 CI 3.3, 27.2) were significantly associated with the occurrence of hypoglycemia in the neonatal intensive care. The proportion of hypoglycemia and associated factors among preterm neonates admitted to the neonatal intensive care unit at Debre Tabor Comprehensive Specialized Hospital was found to be high. The associated factors for the occurrence of hypoglycemia were discovered to be neonates with hypothermia, birth asphyxia, seizure, and neonates born with a diabetes mother. Thus, recognizing and treating the above associated factors is essential to preventing, and controlling hypoglycemia.

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Neonatal hypoglycaemia: prevalence and clinical manifestations in Port Harcourt, Nigeria

Cited by 7 publications

References 0 publications

Prevalence of Hypoglycaemia in Newborn at Benue State University Teaching Hospital, Makurdi, Benue State, Nigeria

Prevalence of Hypoglycaemia in Newborn at Benue State University Teaching Hospital, Makurdi, Benue State, Nigeria

Prevalence and Risk factors of Hypoglycaemia in Neonates at St. Paul’s Hospital Millennium Medical College Neonatal Intensive Care Unit, Ethiopia: A Cross Sectional Study

Maximizing the detection rate of hypoglycemia among preterm neonates admitted in Neonatal intensive care unit in Ethiopia, 2021

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