Neonatal echocardiograms of macrosomic neonates

Abstract

IVS/PW ratio of macrosomic infants fell outside of the normal range. Macrosomic neonates were found to have an increased SF% secondary to a proportionally smaller LVES volume, regardless of IVS thickness.

Carditrophin-1 (CT-1) level and Echocardiographic changes in macrosomic neonate infants

“…This is in agreement with [11] who observed that cardiac diameters were more in macrosomic than control ,also more in macrosomic of IDM than those of non IDM. To the contrary to our results, a study was done by [12] on 9 healthy full term AGA neonates and 15 macrosomic neonates; Echocardiography was done, and showed a similar cardiac measurement in macrosomic neonates and control except mean LVES volume was smaller in macrosomic neonates than in control which resulted in increased FS (fractional shortening),and this could be attributed to a small sample size in their study.…”

“…In the current study: in macrosomic neonates males were (28) represent of cases 70% of cases while females were (12) represented 30%; All neonates in our study were full term with range from 37 to 40 week of gestational age, Our results are in accordance with results of [7] .…”

Intrapartum Fetal Electrocardiogram in Small- and Large-for-Gestational Age Fetuses

“…Large-forgestational age (LGA) fetuses have an increased risk of interventricular septal hypertrophy, cardiomyopathy, cardiac arrhythmias, and biomarkers of myocardial ischemia as compared with those that are appropriate-for-gestational age (AGA). [8][9][10][11] These alterations in cardiac function among LGA infants have been reported both in utero and postnatally, even in the absence of maternal diabetes. [9][10][11][12][13][14][15] Electrocardiographic ST-segment analysis provides a measure of myocardial ischemia.…”

“…[8][9][10][11] These alterations in cardiac function among LGA infants have been reported both in utero and postnatally, even in the absence of maternal diabetes. [9][10][11][12][13][14][15] Electrocardiographic ST-segment analysis provides a measure of myocardial ischemia. [16][17][18] In the setting of fetal cardiac hypoxia, ST-depression and ST-elevation can occur as a result of abnormal repolarization of the myocardium.…”

“…Neonates exhibiting abnormal growth, both small-for-gestational age (<10th percentile for birth weight) and large-forgestational age (>90th percentile for birth weight), are at increased risk of cardiac dysfunction compared with appropriate-for-gestational age neonates (10-90th percentile for birth weight). [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] Several prospective studies have demonstrated altered cardiovascular parameters and signs of myocardial cell damage in infants with fetal growth restriction (FGR) or small-for-gestational age (SGA), some of which may persist after birth and into early childhood. [1][2][3][4][5][6][7] In these studies, FGR was variably defined by fetal biometry characteristics such as an estimated fetal weight <10%, abdominal circumference <5%, or some combination of biometry and abnormal fetal umbilical artery Doppler studies.…”