Neonatal bilateral chylothorax treated by octreotide

Alshafei, Atef; Ahmed, Mahmoud Galal; Khan, Anwar; Gouda, Ahmed

doi:10.7707/hmj.721

Cited by 2 publications

(3 citation statements)

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“…According to Downie et al (2014), patients with chylous pleural effusions who do not meet the requirements of lymphocyte-predominant, protein-discordant exudate should have their secondary causes of chylothorax further assessed. Ahmed et al (2018) state that pseudo-chylothorax typically arises from cholesterol crystal development in long-standing pleural effusions without interfering with the thoracic duct. In pseudochylothorax, but not in chylothorax, adding 1-2 mL of ethyl ether can remove the "milky" look; in empyema, however, the turbidity is caused by suspended pus cells, resulting in a clear supernatant after centrifugation.…”

Section: Resultsmentioning

confidence: 99%

Chylothorax: Approaches to Diagnosis and Treatment

Hari Nastiti,

Sekarsari,

Setyaningrum

et al. 2024

ijsh

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Chylothorax is a rare disease and epidemiologically is most commonly found in children. It can also result in severe respiratory morbidity such as pleural effusion and has a high mortality rate in children. Conservative treatment and consideration of surgical intervention may be warranted as the primary goal of chylothorax management is to remove fluid accumulation in the pleural cavity, avoid recurrence, treat associated problems, and find the underlying cause while maintaining optimal nutrition. We report two cases of chylothorax in children. Data were collected retrospectively from children diagnosed with chylothorax in the pediatric ward of RSUD Dr. Soetomo in 2022. This is a series of cases that includes two children diagnosed with chylothorax. case series involving two patients who underwent cardiac and congenital thoracic surgery and developed chylothorax. Patients receiving partial parenteral nutrition with MCT have improved drainage outcomes. After birth, thoracentesis closes the thoracic drainage, and life support is usually necessary for babies with chylothorax because they often have poor cardiopulmonary function

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Section: Resultsmentioning

confidence: 99%

Chylothorax: Approaches to Diagnosis and Treatment

Hari Nastiti,

Sekarsari,

Setyaningrum

et al. 2024

ijsh

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“…Tropicamide has a lower affinity for systemic muscarinic receptors and not a significant receptor occupancy in plasma which explains why it has no reported vasopressor effect. 5 6 Alpay et al found a significant drop in heart rate after mydriatic drop instillation but no change in blood pressure. 3 While many studies report increment in the heart after mydriatic drops, Bolt et al had found no significant change with the same combination of 2.5% phenylephrine and 0.5% tropicamide.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, these agents may have the potential to cause serious side effects in the presence of systemic absorption. 4 5 6…”

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confidence: 99%

Early Hemodynamic Effects of Mydriatic Eye Drops in Preterm Infants

et al. 2022

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Objective Mydriatic eye drops used for retinopathy of prematurity (ROP) examination can cause systemic effects, and there are case reports of serious adverse effects in the literature. In this prospective study, we aimed to evaluate the early hemodynamic effects of mydriatic eye drops to understand the possible mechanisms of adverse effects. Study Design Between December 2018 and March 2019, preterm babies less than 32 gestational weeks and who underwent ophthalmologic examination in our unit were included. The vital signs (heart rate, respiratory rate, SpO2, blood pressure values), cerebral and mesenteric tissue saturation by near-infrared spectroscopy (NIRS), and left ventricular functions of infants were recorded before and after applying mydriatic eye drops (2.5% phenylephrine and 0.5% tropicamide). The data were compared statistically. Strict adherence to prevent systemic absorption of the eye drops was applied. Results Thirty-two mydriasis procedures were evaluated in 26 patients. The mean gestational age was 28.5±1.7 weeks, and the mean birth weight was 943±233 grams. There were no significant differences in terms of vital signs of infants including heart rate, blood pressure, and SpO2 levels before and after eye drop application. In addition, NIRS values showed no significant differences between before and after measurements. No significant differences were detected at echocardiographic evaluation performed before and after mydriatic administration. No adverse reaction was observed in the study population during the study. Conclusions This is the first study that evaluated the early hemodynamic effects of mydriatic eye drops used for ROP screening by vital signs, NIRS and echocardiographic evaluation. Mydriatic eye drops have no significant effect on early hemodynamic parameters including vital signs, NIRS and echocardiographic findings in preterm infants. We suggest that a cautious approach for avoiding the systemic absorption of these agents may prevent the possible early systemic effects in this high risk population.

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Neonatal bilateral chylothorax treated by octreotide

Cited by 2 publications

References 0 publications

Chylothorax: Approaches to Diagnosis and Treatment

Chylothorax: Approaches to Diagnosis and Treatment

Early Hemodynamic Effects of Mydriatic Eye Drops in Preterm Infants

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