Neonatal bacterial meningitis in southern taiwan

Chang, Cheng-Jong; Chang, Wen-Neng; Huang, Laura; Huang, Song‐Chei; Chang, Ying-Chao; Hung, Po-Cheng; Tasi, Chin-Yen; Lu, Cheng-Hsien; Cheng, Ben-Chung; Lee, Ping-Yu; Chang, Hsueh‐Wen

doi:10.1016/s0887-8994(03)00273-x

Cited by 29 publications

(29 citation statements)

References 26 publications

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“…The average birthweight was 2476.5±774.2 grams and the average gestational age was 36.7±3.4 weeks. These findings were quite different from a study in Taiwan by Chang et al, 5 who found that the average birthweight and gestational age were 3093.5±500.4 grams and 38.9±1.9 weeks, respectively. These differences can be explained from the amount of preterm babies included in both studies.…”

Section: Discussioncontrasting

confidence: 99%

“…4,7,10,11 In Asia, namely Taiwan, also had GBS and E. Coli as the major cause for sepsis and meningitis in neonates. 5 Reports from poor and developing countries, like Nigeria and Ethiopia, showed Gram negative organisms, such as E. coli, Klebsiella, and Enterobacter were the top agents that cause neonatal meningitis. 12,13 In other developing countries, such as Panama and Haiti, although Gram negative organisms (E. coli, Klebsiella, Enterobacter, Serratia, and Pseudomonas) were still in the top charts for causing neonatal meningitis, the incidence of GBS infection tends to increase.…”

Section: Discussionmentioning

confidence: 99%

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Etiological patterns of bacterial meningitis in neonatal sepsis

Setiawan¹,

Amir²,

Tumbelaka³

2016

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Background Sepsis and meningitis are major causes of mortalityand morbidity in neonates. The prevalence of sepsis is around 1-4out of every 1000 live births, and one-fourth is accompanied bymeningitis. These numbers are higher in prematures.Objective To find out the prevalence and etiological patterns ofbacterial meningitis in neonatal sepsis, and the pattern of antibi-otic susceptibility for organisms causing bacterial meningitis.Methods This was a cross sectional study, conducted in the neo-natal ward and emergency room at Cipto Mangunkusumo Hospi-tal from October 2003 to October 2004.Results Seventy two neonates fulfilled the inclusion criteria andwere examined for blood and cerebrospinal fluid (CSF) cultures.Sixty out of 72 neonates were proven for sepsis. Bacterial menin-gitis was found in 18 neonates, and all cases were accompaniedby sepsis. Positive CSF cultures were found in 12 neonates. Theother six were diagnosed based on CSF cell count >32/μl.Acinetobacter calcoaceticus was the major causative organismsin this study. The organisms were highly resistant to first line anti-biotics, except for chloramphenicol. They were also sensitive toceftazidime (second line), meropenem, and imipenem.Conclusions The prevalence of bacterial meningitis in neonatalsepsis at Cipto Mangunkusumo Hospital was 18/60 in 2003-2004.The major causative organism was Acinetobacter calcoaceticus.Antibiotic resistance was very high and only chloramphenicol,ceftazidime, meropenem, and imipenem remain effective

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Etiological patterns of bacterial meningitis in neonatal sepsis

Setiawan¹,

Amir²,

Tumbelaka³

2016

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“…There are different aspects during the birth and the pregnancy care that have been indicated as risk factors for severe infections in newborns [22,23].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of newborn bacterial meningitis and sepsis during the pregnancy period for public health care system participants in Salvador, Bahia, Brazil

Silva¹,

Cavalheiro²,

Queirós³

et al. 2007

Braz J Infect Dis

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Bacterial meningitis is still a major public health threat inside developing countries. In Brazil, the Department of Public Health estimates that the prevalence of bacterial meningitis is 22 cases per 100,000 persons. During the neonatal period, the bacterial meningitis develops special characteristics that can result in hearing problems and movement loss due to neurological and psychological damages. This study had the aim to analyze the prevalence of bacterial meningitis and sepsis in newborns during the pregnancy period for those using the public health care system in Salvador-Bahia. One of the goal was to describe the risk factors of bacterial meningitis and sepsis in newborns. A second goal was to identify, based on newborn health records, the difficulties to predict issues with the hearing, neurological and psychological problems. This study has a cross-sectional design. The newborns that were included in this study had bacterial meningitis or sepsis within 0-28 days of life. They were admitted in the maternity wards between June-December 2005 at the newborn intensive unit care. We analyzed 72 reports of newborns and only 11 (17%) were bacterial meningitis or sepsis newborn cases. These cases were associated to high intake of ototoxic drugs that can cause oto and nephrotoxicity, and cause serious sequels on the child development. Nervous system infection is one of the 2 major problems in clinical practice, especially during the first month after birth. During this first month, the nervous system infection develops special characteristics, which are different from regular symptoms and it requires treatment due to the increased risk to develop complications. It is strongly recommended to monitor ototoxic drugs use to prevent effects on the hearing system. Key-Words: Newborn meningitis, sepsis, prevalence, prediction, complications.The neonatal meningitis is an illness characterized as a result of infection and inflammation of the meninges and it typically happens between birth and the first 28 days of life [1].The bacterial infection is more common during the first month after birth compared to other stages of newborns. It has an incidence that varies from 0.22 to 2.66/1,000 newborns in different countries and it tends to be more common in developing countries [2].During the neonatal period, the illness has special characteristics. The etiology, the clinical symptoms and the mortality appear to be different from the observed in older children [3].The mortality varies based on the treatment, with survival rates of 17% to 29% and with complications rate of 15% to 68%. Among the predictive factors for determining the diagnosis of this condition are the premature birth, newborn weight, type of bacteria, predisposition for the microbial germ, the length of the treatment and complications [4].Although there have been medical advances of medicines and preventive medicine, the incidence of newborn bacterial meningitis for the last 30 years has been barely affected. This minor change in the incidence can be linked po...

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“…The Americas Trotman et al 44 Castrodale et al 45 Hyde et al 47 Mayor-Lynn et al 48 Phares et al 49 Puopolo et al 50 Brooks et al 54 Cordero et al 55 Jordan et al 56 Subtotal (I 2 =86·7%, p=0·000) Africa Gray et al 58 Milledge et al 73 Sigauque et al 74 Subtotal (I 2 =59·9%, p=0·083) Western Pacific Matsubara et al 75 Park et al 96 Cho et al 77 Chang et al 78 …”

Section: Year Europementioning

confidence: 99%

Group B streptococcal disease in infants aged younger than 3 months: systematic review and meta-analysis

Edmond¹,

Kortsalioudaki²,

Scott³

et al. 2012

The Lancet

528

457

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SummaryBackground Despite widespread use of intrapartum antibiotic prophylaxis, group B streptococcus remains a leading cause of morbidity and mortality in infants in Europe, the Americas, and Australia. However, estimates of disease burden in many countries outside of these regions is not available. We aimed to examine the current global burden of invasive disease and the serotype distribution of group B streptococcus isolates.

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Neonatal bacterial meningitis in southern taiwan

Cited by 29 publications

References 26 publications

Etiological patterns of bacterial meningitis in neonatal sepsis

Etiological patterns of bacterial meningitis in neonatal sepsis

Prevalence of newborn bacterial meningitis and sepsis during the pregnancy period for public health care system participants in Salvador, Bahia, Brazil

Group B streptococcal disease in infants aged younger than 3 months: systematic review and meta-analysis

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