Neonatal auditory activation detected by functional magnetic resonance imaging

Anderson, Adam W.; Marois, René; Colson, Eve R.; Peterson, Bradley S.; Duncan, Charles C.; Ehrenkranz, Richard A.; Schneider, Karen; Gore, John C.; Ment, Laura R.

doi:10.1016/s0730-725x(00)00231-9

Cited by 153 publications

(120 citation statements)

References 23 publications

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“…Moreover, somatosensory areas in sedated infants were activated bilaterally in response to a unilateral, passive extension and flexion of the hand (24). In the case of auditory perception, activity in the temporal lobe has been reported for both simple tone stimuli in sleeping infants (25) as well as for speech processing in awake infants (26,27). Our findings regarding resting-state activity together with previous results showing task-evoked responses are in agreement with positron-emission tomography investigations that have shown the highest degree of glucose metabolism in the primary sensory regions of the infant brain (28,29).…”

Section: Discussionmentioning

confidence: 96%

Resting-state networks in the infant brain

Fransson

Skiöld²,

Horsch³

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

591

527

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In the absence of any overt task performance, it has been shown that spontaneous, intrinsic brain activity is expressed as systemwide, resting-state networks in the adult brain. However, the route to adult patterns of resting-state activity through neuronal development in the human brain is currently unknown. Therefore, we used functional MRI to map patterns of resting-state activity in infants during sleep. We found five unique resting-states networks in the infant brain that encompassed the primary visual cortex, bilateral sensorimotor areas, bilateral auditory cortex, a network including the precuneus area, lateral parietal cortex, and the cerebellum as well as an anterior network that incorporated the medial and dorsolateral prefrontal cortex. These results suggest that resting-state networks driven by spontaneous signal fluctuations are present already in the infant brain. The potential link between the emergence of behavior and patterns of resting-state activity in the infant brain is discussed.development ͉ functional MRI ͉ spontaneous activity R ecent research on functional connectivity in the brain, in particular during resting-state conditions, has come to focus on low-frequency (Ͻ0.1 Hz), spontaneous fluctuations in the functional MRI (fMRI) signal. Discovered by Biswal et al. (1), it has been shown that systemwide networks in the resting brain are synchronized in time through intrinsic low-frequency signal fluctuations. Whereas early fMRI studies demonstrated synchronicity of intrinsic brain activity across hemispheres in primary sensory cortices (2, 3), succeeding studies have shown temporal synchronization in a resting-state network encompassing higher-order cortices (4). A systematic investigation of resting-state activity in the adult human brain was recently presented by Damoiseaux et al. (5). Using independentcomponent analysis (ICA), a data-driven explorative data analysis approach, they showed that there are numerous networks in the brain that are driven by spontaneous activity. Besides networks that are in part or fully described by the previously reported default mode (6) and task-positive network (7, 8), they found consistent patterns of resting-state activity in the visual cortex, sensorimotor areas, auditory areas, as well as extrastriate brain regions. These findings together with previous investigations on spontaneous activity suggest that the assumption that the brain during rest is idle and waiting to be triggered and respond to changes in the environment is not strictly valid. Rather, in addition to responding to changes in external stimuli or tasks, the brain is characterized by intrinsic dynamics in the form of coherent and spontaneous fluctuations, clustered together in networks that are credible from an anatomical and functional perspective.Interestingly, recent studies have presented evidence that spontaneous activity is relevant for human behavior. Momentary lapses of attention, affecting goal-oriented behavior on a global/ local selective attention task, were related to a fai...

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Section: Discussionmentioning

confidence: 96%

Resting-state networks in the infant brain

Fransson

Skiöld²,

Horsch³

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

591

527

View full text Add to dashboard Cite

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“…Much of our present-day knowledge about brain-behavior relationships shortly after birth comes from task-based fMRI studies (Allievi et al, 2016;Anderson et al, 2001;Arichi et al, 2013Arichi et al, , 2012Arichi et al, , 2010Born et al, 1996;Dehaene-Lambertz et al, 2010, 2002Erberich et al, 2006;Heep et al, 2009;Konishi et al, 2002;Morita et al, 2000). These studies have provided important background on the brain's responses to sensory input during the earliest phases of development of brain-behavior interactions.…”

Section: Functional Connectivity and Behavioral Counterpartsmentioning

confidence: 99%

“…These studies have provided important background on the brain's responses to sensory input during the earliest phases of development of brain-behavior interactions. Adult-like activation patterns were observed in response to a variety of sensory stimuli, including tactile and proprioceptive stimulation (passive hand movement) (Arichi et al, , 2010Erberich et al, 2006), auditory (Anderson et al, 2001), olfactory (the odor of infant formula) ) and visual input. fMRI studies in two-to three-month-old infants demonstrated leftlateralized activation of perisylvian regions including the superior temporal gyrus, angular gyrus and Broca's area in response to native-language speech (Dehaene-Lambertz et al, 2006, 2002.…”

Section: Functional Connectivity and Behavioral Counterpartsmentioning

confidence: 99%

The emergence of functional architecture during early brain development

2017

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Early human brain development constitutes a sequence of intricate processes resulting in the ontogeny of functionally operative neural circuits. Developmental trajectories of early brain network formation are genetically programmed and can be modified by epigenetic and environmental influences. Such alterations may exert profound effects on neurodevelopment, potentially persisting throughout the lifespan. This review focuses on the critical period of fetal and early postnatal brain development. Here we collate findings from neuroimaging studies, with a particular focus on functional MRI research that interrogated early brain network development in both health and high-risk or disease states. First, we will provide an overview of the developmental processes that take place from the embryonic period through early infancy in order to contextualize brain network formation. Second, functional brain network development in the typically developing brain will be discussed. Third, we will touch on prenatal and perinatal risk factors that may interfere with the trajectories of functional brain wiring, including prenatal substance exposure, maternal mental illness and preterm

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“…We used functional MRI (fMRI) to investigate the neural correlates of music processing in neonates. In recent years, fMRI has been used successfully with pediatric and healthy infant populations (6)(7)(8), proving to be a noninvasive and reliable technique yielding valuable information about brain development. The babies who participated in the study were first exposed to music initially outside the uterine environment, allowing observation of the early developmental stages of a capacity that plays an important role for emotional, cognitive, and social development from the first days of life (9).…”

mentioning

confidence: 99%

Functional specializations for music processing in the human newborn brain

Perani

Saccuman

Scifo

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

285

175

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In adults, specific neural systems with right-hemispheric weighting are necessary to process pitch, melody, and harmony as well as structure and meaning emerging from musical sequences. It is not known to what extent the specialization of these systems results from longterm exposure to music or from neurobiological constraints. One way to address this question is to examine how these systems function at birth, when auditory experience is minimal. We used functional MRI to measure brain activity in 1-to 3-day-old newborns while they heard excerpts of Western tonal music and altered versions of the same excerpts. Altered versions either included changes of the tonal key or were permanently dissonant. Music evoked predominantly right-hemispheric activations in primary and higher order auditory cortex. During presentation of the altered excerpts, hemodynamic responses were significantly reduced in the right auditory cortex, and activations emerged in the left inferior frontal cortex and limbic structures. These results demonstrate that the infant brain shows a hemispheric specialization in processing music as early as the first postnatal hours. Results also indicate that the neural architecture underlying music processing in newborns is sensitive to changes in tonal key as well as to differences in consonance and dissonance.auditory cortex | functional MRI | neonates | emotion

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Neonatal auditory activation detected by functional magnetic resonance imaging

Cited by 153 publications

References 23 publications

Resting-state networks in the infant brain

Resting-state networks in the infant brain

The emergence of functional architecture during early brain development

Functional specializations for music processing in the human newborn brain

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