“…1,3,4 The routine use of surgical staplers does not result in adequate sealing in the majority of patients, 2,16 which leads to prolonged chest tube drainage time, increasing the patient's risk of pleural infections, pulmonary embolism, respiratory distress, and associated pain, therefore prolonging hospital stay. 3,13 Many procedures, such as the application of fibrin glue, [17][18][19] synthetic sealant, 20,21 and biodegradable sealant 22,23 reinforcement of pulmonary closure with various materials, 24,25 and the use of laser, 26,27 ultrasonic dissection, 28 and autologous blood patch 10 have been proposed to control and prevent air leaks (Table 3).…”