2005
DOI: 10.1590/s0365-05962005000100005
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Abstract: FUNDAMENTO: A utilização de antimicrobianos no tratamento da gonorréia iniciou-se em 1930 com as sulfonamidas. No decorrer dos anos outras drogas passaram a ser utilizadas, entre elas a tetraciclina. Embora eficaz no início, esta droga, ao longo do tempo, passou a não mais apresentar o resultado terapêutico esperado em virtude do aparecimento de quadros de resistência cromossômica e plasmidial em diversos países. Como a tetraciclina ainda continua sendo indicada, isoladamente ou associada a outras drogas antim… Show more

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Cited by 6 publications
(4 citation statements)
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“…In an individual in a state of anergy, such as lepromatous leprosy and anergic cutaneous leishmaniasis patients, the cytokines produced by macrophages act on the Th2 subpopulation, which produces IL-4, IL-5, IL-10, and IL-13, which suppress macrophage activity and stimulate B lymphocytes and mast cells, thus configuring the humoral immune response. 5 - 7 Thus, individuals with a Th1 immune profile are more resistant to infection because they present a more intense and effective cellular immune response, whereas individuals with Th2 immune profile are more susceptible. 5 - 7 …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In an individual in a state of anergy, such as lepromatous leprosy and anergic cutaneous leishmaniasis patients, the cytokines produced by macrophages act on the Th2 subpopulation, which produces IL-4, IL-5, IL-10, and IL-13, which suppress macrophage activity and stimulate B lymphocytes and mast cells, thus configuring the humoral immune response. 5 - 7 Thus, individuals with a Th1 immune profile are more resistant to infection because they present a more intense and effective cellular immune response, whereas individuals with Th2 immune profile are more susceptible. 5 - 7 …”
Section: Discussionmentioning
confidence: 99%
“… 5 - 7 Thus, individuals with a Th1 immune profile are more resistant to infection because they present a more intense and effective cellular immune response, whereas individuals with Th2 immune profile are more susceptible. 5 - 7 …”
Section: Discussionmentioning
confidence: 99%
“…Esse processo agressivo pode ser súbito, porém geralmente decorre de um quadro de evolução da psoríase vulgar. Visto seu caráter sistêmico, os pacientes devem receber tratamentos que minimizem os riscos de evolução para condições potencialmente fatais, como insuficiência cardíaca e infecções respiratórias (pneumonias) (BELDA et al, 2018). A psoríase invertida (Figura 2.4) acomete as regiões de dobras e flexuras, como axilas, umbigo, fossas poplíteas, dobras antecubitais e inguinais.…”
Section: Fisiopatologia E Manifestações Clínicasunclassified
“…Such a condition can therefore greatly impair the affected person's appearance and have a negative impact on their quality of life (QoL). 2 …”
Section: Introductionmentioning
confidence: 99%