Neisseria gonorrhoeae produtora de penicilinase: primeira cepa isolada em São Paulo, SP (Brasil)

Lombardi, Clovis; Siqueira, Luiz Fernando de Góes; Júnior, Manuel Fernando Queiroz dos Santos; Francisco, Waldemar; Belda, Walter

doi:10.1590/s0034-89101985000400009

Rev. Saúde Pública

1985

DOI: 10.1590/s0034-89101985000400009

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Neisseria gonorrhoeae produtora de penicilinase: primeira cepa isolada em São Paulo, SP (Brasil)

Clovis Lombardi

Luiz Fernando de Góes Siqueira

Manuel Fernando Queiroz dos Santos Júnior

et al.

Abstract: Relata-se o primeiro caso identificado de Neisseria gonorrhoeae produtora de penicilinase (NGPP) no Estado de São Paulo, Brasil, demonstrando a necessidade de mensurar os índices de prevalência destas cepas na população.

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Reduced Susceptibility to Azithromycin and High Percentages of Penicillin and Tetracycline Resistance in Neisseria gonorrhoeae Isolates from Manaus, Brazil, 1998

Jp²,

As³

et al. 2001

Sexually Transmitted Diseases

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This study supports the continued use of third-generation cephalosporins, spectinomycin, and fluoroquinolone drugs for the primary treatment of gonococcal infections in Manaus. The occurrence of isolates with reduced susceptibility to azithromycin and ciprofloxacin underscores the importance of ongoing antimicrobial susceptibility monitoring to support decisions regarding appropriate drugs for the treatment of gonococcal infections.

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Reduced Susceptibility to Azithromycin and High Percentages of Penicillin and Tetracycline Resistance in Neisseria gonorrhoeae Isolates from Manaus, Brazil, 1998

Jp²,

As³

et al. 2001

Sexually Transmitted Diseases

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show abstract

Effectiveness of syndromic management for male patients with urethral discharge symptoms in Amazonas, Brazil

Filho

Sardinha²,

Galbán³

et al. 2017

An. Bras. Dermatol.

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BackgroundUrethral discharge syndrome (UDS) is characterized by the presence of purulent or mucopurulent urethral discharge.The main etiological agents of this syndrome are Neisseria gonorrhoeae and Chlamydia trachomatis.ObjectivesTo evaluate the effectiveness of the syndromic management to resolve symptoms in male urethral discharge syndrome cases in Manaus, Amazonas, Brazil.MethodsRetrospective cohort of male cases of urethral discharge syndrome observed at a clinic for sexually transmitted disease (STD) in 2013. Epidemiological and clinical data, as well as the results of urethral swabs, bacterioscopy, hybrid capture for C.trachomatis, wet-mount examination, and culture for N.gonorrhoeae, were obtained through medical chart reviews.ResultsOf the 800 urethral discharge syndrome cases observed at the STD clinic, 785 (98.1%) presented only urethral discharge syndrome, 633 (79.1%) returned for follow-up, 579 (91.5%) were considered clinically cured on the first visit, 41(6.5 %) were considered cured on the second visit, and 13(2.0%) did not reach clinical cure after two appointments. Regarding the etiological diagnosis, 42.7% of the patients presented a microbiological diagnosis of N.gonorrhoeae, 39.3% of non-gonococcal and non-chlamydia urethritis, 10.7% of C.trachomatis and 7.3% of co-infection with chlamydia and gonococcus. The odds of being considered cured in the first visit were greater in those who were unmarried, with greater schooling, and with an etiological diagnosis of gonorrhea. The diagnosis of non-gonococcal urethritis reduced the chance of cure in the first visit.Study limitationA study conducted at a single center of STD treatment.ConclusionSyndromic management of male urethral discharge syndrome performed in accordance with the Brazilian Ministry of Health STD guidelines was effective in resolving symptoms in the studied population. More studies with microbiological outcomes are needed to ensure the maintenance of the syndromic management.

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Neisseria gonorrhoeae produtora de penicilinase: primeira cepa isolada em São Paulo, SP (Brasil)

Abstract: Relata-se o primeiro caso identificado de Neisseria gonorrhoeae produtora de penicilinase (NGPP) no Estado de São Paulo, Brasil, demonstrando a necessidade de mensurar os índices de prevalência destas cepas na população.

Cited by 2 publications

References 1 publication

Reduced Susceptibility to Azithromycin and High Percentages of Penicillin and Tetracycline Resistance in Neisseria gonorrhoeae Isolates from Manaus, Brazil, 1998

Reduced Susceptibility to Azithromycin and High Percentages of Penicillin and Tetracycline Resistance in Neisseria gonorrhoeae Isolates from Manaus, Brazil, 1998

Effectiveness of syndromic management for male patients with urethral discharge symptoms in Amazonas, Brazil

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