Neighbouring group effects on rates of thermolysis of 4-azidothiazoles

Theoretical Studies on N–O or N–N Bond Formation from Aryl Azide Catalyzed by Iron(II) Bromide Complex

“…An attempt to locate such a stepwise transition state was not successful, and only TS (1–2)A was obtained. About the concerted mechanism, our calculations are consistent with the thermolysis of aryl azides in previous reports, which described a concerted loss of N 2 and ring closure. − …”

Synthesis of condensed thiazoles. (Review)

“…The most general method for their synthesis is probably the cyclization of geminal azido imines 18. Thus, pyrazolo [3,4-d]thiazoles 19 were synthesized with yields of 80% by heating in toluene the Schiff bases 18, which were in turn obtained by the reaction of the corresponding 4-azidothiazolecarbaldehydes with various substituted anilides [22,23]. …”