Negligible absorption of radiofrequency radiation by colloidal gold nanoparticles

Li, Dongxiao; Jung, Yun Suk; Tan, Susheng; Kim, Hong Koo; Chory, Eamon; Geller, David A.

doi:10.1016/j.jcis.2011.01.059

Cited by 63 publications

(99 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The purpose of this paper is to show that absorption of MHz through low THz radiation by individual, noninteracting, spherical metallic nanoparticles is negligible and produces no substantial heating and, further, that the heating is so insignificant that even very large collections of nanoparticles cannot lead to heating of the suspension, supporting the conclusions of Ref. 13. To this end, we analyze several mechanisms by which nonmagnetic metallic nanoparticles can absorb low frequency radiation, namely, (i) the classical prediction of Mie theory for the absorption of electromagnetic energy by small spheres, including the possibility that the spheres are coated by an absorbing material, and (ii) electronic absorption occurring at the surface of the spheres due to electron spillout, surface roughness, and effects of surface phonons.…”

Section: Introductionsupporting

confidence: 76%

“…In Ref. 13, the observed RF heating was completely attributed to Joule heating of the ionic host medium. The authors also argue that this mechanism is likely responsible for the heating observed in Refs.…”

Section: Thermodynamical Analysismentioning

confidence: 99%

“…A series of papers [4][5][6][7][8][9][10][11][12] has considered RF heating of gold nanoparticles, showing significant heating. However, a recent experiment 13 contradicts this, and finds that gold nanoparticles at RF do not heat. It was concluded that at RF the observed heating was due to Joule heating of the ionic stock solution which housed the nanoparticles.…”

Section: Introductionmentioning

confidence: 97%

See 2 more Smart Citations

Electromagnetic absorption mechanisms in metal nanospheres: Bulk and surface effects in radiofrequency-terahertz heating of nanoparticles

Hanson

Monreal

Apell

2011

Journal of Applied Physics

View full text Add to dashboard Cite

We report on the absorption of electromagnetic radiation by metallic nanoparticles in the radio and far infrared frequency range, and subsequent heating of nanoparticle solutions. A recent series of papers has measured considerable radio frequency (RF) heating of gold nanoparticle solutions. In this work, we show that claims of RF heating by metallic nanoparticles are not supported by theory. We analyze several mechanisms by which nonmagnetic metallic nanoparticles can absorb low frequency radiation, including both classical and quantum effects. We conclude that none of these absorption mechanisms, nor any combination of them, can increase temperatures at the rates recently reported. A recent experiment supports this finding.

show abstract

Section: Introductionsupporting

confidence: 76%

Section: Thermodynamical Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

See 1 more Smart Citation

Electromagnetic absorption mechanisms in metal nanospheres: Bulk and surface effects in radiofrequency-terahertz heating of nanoparticles

Hanson

Monreal

Apell

2011

Journal of Applied Physics

View full text Add to dashboard Cite

show abstract

“…Recently, GNPs have been proposed for non-invasive radiofrequency (RF) hyperthermia treatment of cancer. [7][8][9][10][11][12][13][14][15] The basic idea of this hypothesis includes a few steps: (i) GNPs coated with peptides or molecules that can detect cancer cells are injected into cancerous tissue; (ii) After GNPs attaching on the membrane of cancer cells, RF fields are applied to tissues incubated with GNPs; and (iii) GNPs absorb RF energy and heat up, inducing the hyperthermia effect. It is normally required that the regional high temperature needs to be >42 C to cause any lethal effect to cancer cells.…”

Section: Introductionmentioning

confidence: 99%

“…Moran 9 reported a size-dependent heating effect of GNP colloids and attributed this phenomenon to the Joule heating. Later on, Li 13 and Liu 14 experimentally reported that the heating effect of GNP colloids was not due to the presence of GNPs, but the ionic impurities within the colloid. Theoretically, Hanson 17 investigated the heating mechanisms of GNPs from various aspects, including the dielectric loss, phonon transfer, and the surface electron effect, and concluded that naked GNPs could not be heated by 13.56 MHz RF field.…”

Section: Introductionmentioning

confidence: 99%

Electromagnetic heating effect of aggregated gold nanoparticle colloids

Liu

Chen

et al. 2014

Journal of Applied Physics

View full text Add to dashboard Cite

Gold nanoparticles (GNPs) have been recently investigated intensively for potential hyperthermia treatment of malignant cancer cells in combination with radiofrequency (RF) electromagnetic (EM) fields/waves. However, many controversial results have been reported on whether GNPs can be heated by EM fields. It has been suggested that aggregated GNPs may be heated significantly by a RF field, which however has not been examined experimentally. This work proposes a novel electric treatment of mono-dispersed particles to create aggregated GNPs, and conducts an investigation of their bulk heating behavior under a 655 nm laser and a 13.56 MHz RF electric field. It is revealed that the heating rates of aggregated colloids are significantly higher than those of mono-dispersed GNPs for the 655 nm laser, whereas at 13.56 MHz, the heating effects are barely noticeable for both aggregated and mono-dispersed colloids. Various possible reasons are discussed and the negligible electric field enhancement is believed to be responsible at 13.56 MHz.

show abstract

Gold Nanoparticle-Based Sensors Activated by External Radio Frequency Fields

Vedova

Ilieva

Zhurbenko

et al. 2014

Small

View full text Add to dashboard Cite

A novel molecular beacon (a nanomachine) is constructed that can be actuated by a radio frequency (RF) field. The nanomachine consists of the following elements arranged in molecular beacon configuration: a gold nanoparticle that acts both as quencher for fluorescence and a localized heat source; one reporter fluorochrome, and; a piece of DNA as a hinge and recognition sequence. When the nanomachines are irradiated with a 3 GHz RF field the fluorescence signal increases due to melting of the stem of the molecular beacon. A control experiment, performed using molecular beacons synthesized by substituting the gold nanoparticle by an organic quencher, shows no increase in fluorescence signal when exposed to the RF field. It may therefore be concluded that the increased fluorescence for the gold nanoparticle-conjugated nanomachines is not due to bulk heating of the solution, but is caused by the presence of the gold nanoparticles and their interaction with the RF field; however, existing models for heating of gold nanoparticles in a RF field are unable to explain the experimental results. Due to the biocompatibility of the construct and RF treatment, the nanomachines may possibly be used inside living cells. In a separate experiment a substantial increase in the dielectric losses can be detected in a RF waveguide setup coupled to a microfluidic channel when gold nanoparticles are added to a low RF loss liquid. This work sheds some light on RF heating of gold nanoparticles, which is a subject of significant controversy in the literature.

show abstract

Negligible absorption of radiofrequency radiation by colloidal gold nanoparticles

Cited by 63 publications

References 24 publications

Electromagnetic absorption mechanisms in metal nanospheres: Bulk and surface effects in radiofrequency-terahertz heating of nanoparticles

Electromagnetic absorption mechanisms in metal nanospheres: Bulk and surface effects in radiofrequency-terahertz heating of nanoparticles

Electromagnetic heating effect of aggregated gold nanoparticle colloids

Gold Nanoparticle-Based Sensors Activated by External Radio Frequency Fields

Contact Info

Product

Resources

About