Negative results in bio-medicine are urgently needed

Abstract

The development of statistical models and blind studies in medicine has changed our view of patient management. Evidence Based Medicine data now provide guidelines for treatment modalities. Meta-analytical studies performed on large populations have consolidated this trend. Are all these factors enough to promote further development in modern biomedical science? It seems not. In bio-medicine, analysis of negative results is valuable and stimulates the development of new methods and techniques

The Promises and Challenges of Tissue Engineering for Urinary Diversion

“…Negative results, if presented properly, can and will have a positive impact on future experimental work. 9 It must be emphasized that Geutjes et al are pioneers in this important field of experimental reconstructive surgery in uro-oncology. Editors must encourage authors to submit well prepared manuscripts that should also contain the negative results of reconstructive urology.…”