Negative pressure wound therapy to prevent seromas and treat surgical incisions after total hip arthroplasty

Pachowsky, Milena; Gusinde, J.; Klein, Andrea; Lehrl, S; Schulz-Drost, Stefan; Schlechtweg, Philipp; Pauser, Josef; Gelse, Kolja; Brem, Matthias

doi:10.1007/s00264-011-1321-8

Cited by 191 publications

(191 citation statements)

References 17 publications

(24 reference statements)

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“…After removal of duplicates, 872 remained. Eighty‐three full‐text papers were retrieved for inspection, of which seven were RCTs33, 34, 35, 36, 37, 38, 39. A further six unpublished studies were identified through contact with manufacturers and by searching ClinicalTrials.gov.…”

Section: Resultsmentioning

confidence: 99%

“…(personal communication), used an NPWT device (VAC®) and six34, 35, 38, 39, including those of S. Karlakki et al . and R. Galiano et al .…”

Section: Resultsmentioning

confidence: 99%

“…The duration of treatment before first change of dressing varied from 2 to 7 (median 5) days in the intervention group and from 1 to 7 (median 2) days in the control group (duration was not stated in 3 studies34, 38, 39). The length of follow‐up varied from 10 days to 1 year.…”

Section: Resultsmentioning

confidence: 99%

“…Three studies, two on hip arthroplasty34, 38 and one on spinal fractures39, reported on seroma. The two studies on hip arthroplasty reported on the presence or absence of seroma.…”

Section: Resultsmentioning

confidence: 99%

“…2 to 8) ( Table 2). All three studies reported the volume of seroma measured by ultrasonography on day 5, and two studies34, 39 reported the volume on day 10. The mean difference between the two groups was −1·97 (95 per cent c.i.…”

Section: Resultsmentioning

confidence: 99%

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Meta-analysis of negative-pressure wound therapy for closed surgical incisions

Hyldig

Birke-Sørensen

Kruse

et al. 2016

British Journal of Surgery

196

172

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BackgroundPostoperative wound complications are common following surgical procedures. Negative‐pressure wound therapy (NPWT) is well recognized for the management of open wounds and has been applied recently to closed surgical incisions. The evidence base to support this intervention is limited. The aim of this study was to assess whether NPWT reduces postoperative wound complications when applied to closed surgical incisions.MethodsThis was a systematic review and meta‐analysis of randomized clinical trials of NPWT compared with standard postoperative dressings on closed surgical incisions.ResultsTen studies met the inclusion criteria, reporting on 1311 incisions in 1089 patients. NPWT was associated with a significant reduction in wound infection (relative risk (RR) 0·54, 95 per cent c.i. 0·33 to 0·89) and seroma formation (RR 0·48, 0·27 to 0·84) compared with standard care. The reduction in wound dehiscence was not significant. The numbers needed to treat were three (seroma), 17 (dehiscence) and 25 (infection). Methodological heterogeneity across studies led to downgrading of the quality of evidence to moderate for infection and seroma, and low for dehiscence.ConclusionCompared with standard postoperative dressings, NPWT significantly reduced the rate of wound infection and seroma when applied to closed surgical wounds. Heterogeneity between the included studies means that no general recommendations can be made yet.

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Section: Resultsmentioning

confidence: 99%

“…(personal communication), used an NPWT device (VAC®) and six34, 35, 38, 39, including those of S. Karlakki et al . and R. Galiano et al .…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Three studies, two on hip arthroplasty34, 38 and one on spinal fractures39, reported on seroma. The two studies on hip arthroplasty reported on the presence or absence of seroma.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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